Evidence map›Paper›PMID 33755255›Full record

ArticleJournal of veterinary internal medicine2021

CyberKnife stereotactic radiotherapy for treatment of primary intracranial tumors in dogs.

Gabrielle L Carter, Gregory K Ogilvie, Lenore A Mohammadian, Phillip J Bergman, Rachel P Lee, David R Proulx

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Gabrielle L CarterVCA California Veterinary Specialists, Carlsbad, California, USA.ORCID https://orcid.org/0000-0002-2827-798X
Gregory K OgilvieVCA California Veterinary Specialists, Carlsbad, California, USA.
Lenore A MohammadianVCA California Veterinary Specialists, Carlsbad, California, USA.
Phillip J BergmanVCA Clinical Studies, Los Angeles, California, USA.
Rachel P LeeVCA California Veterinary Specialists, Carlsbad, California, USA.
David R ProulxVCA California Veterinary Specialists, Carlsbad, California, USA.
Carolina Veterinary Specialists · USMuseum of Contemporary Art, Los Angeles · USUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited data exist about the use, efficacy, and prognostic factors influencing outcome when CyberKnife is used to treat dogs with intracranial neoplasia.

objectivesTo determine the prognosis and associated prognostic factors for dogs that were imaged, determined to have primary intracranial tumors, and treated with CyberKnife radiotherapy. ANIMALS: Fifty-nine dogs treated with CyberKnife radiotherapy for primary intracranial tumors.

methodsRetrospective medical record review of cases from January 2010 to June 2016. Data extracted from medical records included signalment, weight, seizure history, tumor location, tumor type (based on imaging), gross tumor volume, planned tumor volume, treatment dates, radiation dose, recurrence, date of death, and cause of death.

resultsThe median progression-free interval (PFI) was 347 days (range 47 to 1529 days), and the median survival time (MST) was 738 days (range 4 to 2079 days). Tumor location was significantly associated with PFI when comparing cerebrum (median PFI 357 days; range 47-1529 days) versus cerebellum (median PFI 97 days; range 97-168 days) versus brainstem (median PFI 266 days; range 30-1484 days), P = .03. Additionally, the presumed tumor type was significantly associated with MST (P < .001). CONCLUSIONS AND CLINICAL IMPORTANCE: Use of Cyberknife and SRT might improve MST, compared with RT, in dogs with intracranial neoplasia.

Indexed as

Brain NeoplasmsDog DiseasesRadiosurgeryAnimalsDogsNeoplasm Recurrence, LocalRetrospective StudiesTreatment Outcomebraincancerdogradiation

Identifiers

PMID33755255
PMCPMC8163137
OpenAlexW3137474479

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.