ArticleMagnetic resonance in medicine2021
Quantitative validation of MRI mapping of cerebral venous oxygenation with direct blood sampling: A graded-O
Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Cerebral oxygen extraction fraction as a physiological biomarker in vascular cognitive impairment: A study in older adults enriched for small vessel diseases.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Diminished Cerebral Oxygen Extraction and Metabolic Rate in Neonates With Hypoxic Ischemic Encephalopathy.Stroke · 2025Article
- Brain Frontal-Lobe Misery Perfusion in COVID-19 ICU Survivors: An MRI Pilot Study.Brain sciences · 2024Article
- Red cell exchange transfusions increase cerebral capillary transit times and may alter oxygen extraction in sickle cell disease.NMR in biomedicine · 2023Article
- Cerebral oxygen extraction fraction MRI: Techniques and applications.Magnetic resonance in medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo validate two neonatal cerebral venous oxygenation (Y
methodsIn vivo experiments were performed on seven healthy newborn piglets. For each piglet, a catheter was placed in the superior sagittal sinus to obtain venous blood samples for blood gas oximetry measurement as a gold standard. During the MRI experiment, three to five venous oxygenation levels were achieved in each piglet by varying inhaled O
resultsThe mean hematocrit was 23.6 ± 6.5% among the piglets. Across all measurements, Y
conclusionThe values of Y
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.