Evidence map›Paper›PMID 33755127›Full record

ArticleInternational journal of epidemiology2021

Transportation noise and risk of stroke: a nationwide prospective cohort study covering Denmark.

Mette Sørensen, Aslak Harbo Poulsen, Ulla Arthur Hvidtfeldt, Thomas Münzel, Jesse Daniel Thacher, Matthias Ketzel, Jørgen Brandt, Jesper H Christensen, Gregor Levin, Ole Raaschou-Nielsen

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in International journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Impact of Residential Noise Exposure on Neurological Health: A Systematic Scoping Review.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
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  15. Perspectives on environment and health research in Denmark.Scandinavian journal of public health · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Mette SørensenDiet, Genes and Environment, Danish Cancer Society Research Center, Strandboulevarden 49, Copenhagen, Denmark.
Aslak Harbo PoulsenDiet, Genes and Environment, Danish Cancer Society Research Center, Strandboulevarden 49, Copenhagen, Denmark.
Ulla Arthur HvidtfeldtDiet, Genes and Environment, Danish Cancer Society Research Center, Strandboulevarden 49, Copenhagen, Denmark.
Thomas MünzelUniversity Medical Center Mainz of the Johannes Gutenberg University, Center for Cardiology, Cardiology I, Langenbeckstrasse 1, Mainz, Germany.
Jesse Daniel ThacherDiet, Genes and Environment, Danish Cancer Society Research Center, Strandboulevarden 49, Copenhagen, Denmark.
Matthias KetzelDepartment of Environmental Science, Aarhus University, Frederiksborgvej 399, Roskilde, Denmark.
Jørgen BrandtDepartment of Environmental Science, Aarhus University, Frederiksborgvej 399, Roskilde, Denmark.
Jesper H ChristensenDepartment of Environmental Science, Aarhus University, Frederiksborgvej 399, Roskilde, Denmark.
Gregor LevinDepartment of Environmental Science, Aarhus University, Frederiksborgvej 399, Roskilde, Denmark.
Ole Raaschou-NielsenDiet, Genes and Environment, Danish Cancer Society Research Center, Strandboulevarden 49, Copenhagen, Denmark.
Danish Cancer Society · DKAarhus University · DKJohannes Gutenberg University Mainz · DEUniversity of Surrey · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies on transportation noise and incident stroke are few and inconclusive. We aimed to investigate associations between road-traffic and railway noise and the risk of incident stroke in the entire Danish population.

methodsWe estimated road-traffic and railway noise (Lden) at the most and least exposed façades for all residential addresses across Denmark (2.8 million) for the period 1990-2017. Based on this, we estimated the 10-year time-weighted mean noise exposure for 3.6 million Danes aged >35 years, of whom 184 523 developed incident stroke during follow-up from 2000 to 2017. Analyses were conducted using Cox proportional-hazards models, with adjustment for various individual- and area-level demographic and socio-economic covariates collected from registries and air pollution [fine particulate matter with particles with a diameter of ≤2.5 µm (PM2.5) and nitrogen dioxide (NO2)].

resultsA 10-dB increase in the 10-year mean road-traffic noise at the most exposed façade was associated with an incidence rate ratio (IRR) of 1.04 [95% confidence interval (CI): 1.03-1.05] for all strokes. For road-traffic noise at the least exposed façade, the IRR per 10 dB was 1.03 (95% CI: 1.02-1.04) for all strokes. Railway noise was not associated with a higher risk of stroke.

conclusionRoad-traffic noise increased the risk of stroke. These findings add to the evidence of road-traffic noise as a cardiovascular risk factor.

Indexed as

Air PollutionNoise, TransportationStrokeDenmarkEnvironmental ExposureHumansProspective Studiesepidemiologyincident strokerailway noiseroad-traffic noiseTransportation noise

Identifiers

PMID33755127
OpenAlexW3137585425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.