Evidence map›Paper›PMID 33755009›Full record

ArticleEmerging infectious diseases2021

Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples.

Anne E Watkins, Eli P Fenichel, Daniel M Weinberger, Chantal B F Vogels, Doug E Brackney, Arnau Casanovas-Massana, Melissa Campbell, John Fournier, Santos Bermejo, Rupak Datta and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Acute SARS-CoV-2 infection.Nature reviews. Disease primers · 2025
    Review
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  20. Safe and effective pool testing for SARS-CoV-2 detection.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Anne E Watkins
Eli P Fenichel
Daniel M Weinberger
Chantal B F Vogels
Doug E Brackney
Arnau Casanovas-Massana
Melissa Campbell
John Fournier
Santos Bermejo
Rupak Datta
Charles S Dela Cruz
Shelli F Farhadian
Akiko Iwasaki
Albert I Ko
Nathan D Grubaugh
Anne L Wyllie
Yale IMPACT Research Team2
Yale University · USConnecticut Agricultural Experiment Station · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
TRAINING IN THE PATHOGENESIS OF INFECTIOUS DISEASEST32AI007517 · NIAID · YALE UNIVERSITY · PI Jaimie Meyer, Albert C Shaw · 1997 to 2026
$6.1M
NCATS NIH HHS UL1 TR001863NIAID NIH HHS T32 AI007517
6 · The paper itself

Abstract

We analyzed feasibility of pooling saliva samples for severe acute respiratory syndrome coronavirus 2 testing and found that sensitivity decreased according to pool size: 5 samples/pool, 7.4% reduction; 10 samples/pool, 11.1%; and 20 samples/pool, 14.8%. When virus prevalence is >2.6%, pools of 5 require fewer tests; when <0.6%, pools of 20 support screening strategies.

Indexed as

COVID-19Capacity BuildingCOVID-19 Nucleic Acid TestingHealth Care RationingHumansLimit of DetectionResource AllocationSalivaSARS-CoV-2Sensitivity and SpecificitySpecimen HandlingUnited States2019 novel coronavirus diseasecoronavirus diseaseCOVID-19diagnosticsrespiratory infectionssalivaSARS-CoV-2screeningsevere acute respiratory syndrome coronavirus 2viruseszoonoses

Identifiers

PMID33755009
PMCPMC8007323
OpenAlexW3135947366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.