Evidence map›Paper›PMID 33754931›Full record

ReviewCurrent medical research and opinion2021

COVID-19 infection and rheumatoid arthritis: mutual outburst cytokines and remedies.

Noha Mousaad Elemam, Azzam A Maghazachi, Suad Hannawi

Abstract readReview
In one paragraph

Review in Current medical research and opinion, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. [Onset of rheumatoid arthritis after SARS-CoV-2 infection].Revista colombiana de reumatologia · 2022
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Noha Mousaad ElemamSharjah Institute for Medical Research, College of Medicine, University of Sharjah, Sharjah, UAE.ORCID 0000-0002-3586-6731
Azzam A MaghazachiSharjah Institute for Medical Research, College of Medicine, University of Sharjah, Sharjah, UAE.ORCID 0000-0002-3310-678X
Suad HannawiDepartment of Rheumatology, Ministry of Health and Prevention, Dubai, UAE.ORCID 0000-0002-5689-6710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In March 2020, COVID-19 infection caused by SARS-CoV-2 has been declared to be a global pandemic, where its complications, severity and mortality are reported to be due to the released inflammatory cytokines or the so-called cytokine storm. This is quite similar to that observed in the autoimmune and chronic inflammatory rheumatic disease, rheumatoid arthritis (RA). It was hypothesized that RA patients are at a higher risk of acquiring COVID-19; however, recent studies reported that they are not when compared to the rest of the population. In this review, we aim to highlight the mutual pathological features, cytokine profiles and risk factors between COVID-19 and RA. Also, many researchers are currently working to explore therapeutic agents that could aid in the eradication of COVID-19 infection. Due to the similarity between the inflammation status in COVID-19 and RA, many anti-rheumatic drugs such as hydroxychloroquine, tocilizumab, baricitinib and anakinra were proposed to be therapeutic modalities for COVID-19 infection.

Indexed as

Arthritis, RheumatoidCOVID-19COVID-19 Drug TreatmentCytokine Release SyndromeAntirheumatic AgentsCytokinesHumansRisk FactorsAntirheumatic AgentsCytokinesanti-rheumaticCOVID-19cytokinesDMARDsRheumatoid arthritis

Identifiers

PMID33754931
PMCPMC8040489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.