Evidence map›Paper›PMID 33754833›Full record

ArticleJournal of the American Heart Association2021

Cigarette Smoking, Incident Coronary Heart Disease, and Coronary Artery Calcification in Black Adults: The Jackson Heart Study.

Adebamike A Oshunbade, Wondwosen Kassahun-Yimer, Karen A Valle, Arsalan Hamid, Rodney K Kipchumba, Daisuke Kamimura, Donald Clark, Wendy B White, Andrew P DeFilippis, Michael J Blaha and 11 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 48 citations in OpenAlex.

  1. Acceptability of Using Large Language Models to Support Smoking Cessation Attempts: a Qualitative Study Among African Americans Who Smoke.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
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  13. Smoking and Coronary Atherosclerosis: Disproportionate Impact on the Right Coronary Artery.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 8 institutions in 2 countries.

Adebamike A OshunbadeDepartment of Medicine University of Mississippi Medical Center Jackson MS.
Wondwosen Kassahun-YimerDepartment of Data Sciences University of Mississippi Medical Center Jackson MS.
Karen A ValleDepartment of Data Sciences University of Mississippi Medical Center Jackson MS.
Arsalan HamidDepartment of Medicine University of Mississippi Medical Center Jackson MS.
Rodney K KipchumbaUniversity of Mississippi Medical Center, School of Medicine Jackson MS.
Daisuke KamimuraDepartment of Medicine University of Mississippi Medical Center Jackson MS.
Donald ClarkDepartment of Medicine University of Mississippi Medical Center Jackson MS.
Wendy B WhiteTougaloo College Jackson MS.
Andrew P DeFilippisDivision of Cardiovascular Medicine University of Louisville KY.
Michael J BlahaJohns Hopkins Ciccarone Center for Prevention of Heart Disease Baltimore MD.
Emelia J BenjaminDepartment of Medicine Boston University School of Medicine Boston MA.
Emily C O'BrienDuke University Medical CenterDuke Clinical Research Institute Durham NC.
Robert J MentzDuke University Medical CenterDuke Clinical Research Institute Durham NC.
Carlos J RodriguezDivision of Cardiology Albert Einstein College of Medicine Bronx NY.
Ervin R FoxDepartment of Medicine University of Mississippi Medical Center Jackson MS.
Javed ButlerDepartment of Medicine University of Mississippi Medical Center Jackson MS.
Rachel J KeithDepartment of Medicine University of Louisville KY.
Aruni BhatnagarDepartment of Medicine University of Louisville KY.
Rose Marie RobertsonDepartment of Medicine Vanderbilt University Medical Center Nashville TN.
Adolfo CorreaDepartment of Medicine University of Mississippi Medical Center Jackson MS.
Michael E HallDepartment of Medicine University of Mississippi Medical Center Jackson MS.
Jackson Memorial Hospital · USUniversity of Louisville · USClinical Research Institute · USAlbert Einstein College of Medicine · USAmerican Heart Association · USBoston University · USJohns Hopkins University · USTougaloo College · US

Funding

Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI GOMEZ-SANCHEZ, CELSO ENRIQUE · 2016 to 2025
$38.2M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI ALEXANDER, BARBARA T · 2013 to 2022
$23.4M
ConProject-006U54HL120163 · NHLBI · AMERICAN HEART ASSOCIATION · PI BHATNAGAR, ARUNI, ROBERTSON, ROSE MARIE · 2018 to 2022
$18.8M
Renal Sinus Fat, Hypertension, and Altered Kidney FunctionK08DK099415 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, MICHAEL EDWARD · 2015 to 2019
$791k
NHLBI NIH HHS HHSN268201800012CNHLBI NIH HHS HHSN268201800012INHLBI NIH HHS HHSN268201800014CNHLBI NIH HHS HHSN268201800014INHLBI NIH HHS HHSN268201800015INHLBI NIH HHS U54 HL120163NIDDK NIH HHS K08 DK099415NIGMS NIH HHS P20 GM104357NIGMS NIH HHS U54 GM115428NIMHD NIH HHS HHSN268201800013I
6 · The paper itself

Abstract

Background Although Black adults are more likely to die from coronary heart disease (CHD) compared with White adults, few studies have examined the relationship between cigarette smoking and CHD risk among Black adults. We evaluated the relationship between cigarette smoking, incident CHD, and coronary artery calcification in the JHS (Jackson Heart Study). Methods and Results We classified JHS participants without a history of CHD (n=4432) by self-reported baseline smoking status into current, former (smoked at least 400 cigarettes/life) or never smokers at baseline (2000-2004). We further classified current smokers by smoking intensity (number of cigarettes smoked per day [1-19 or ≥20]) and followed for incident CHD (through 2016). Hazard ratios (HR) for incident CHD for each smoking group compared with never smokers were estimated with adjusted Cox proportional hazard regression models. At baseline, there were 548 (12.4%) current, 782 (17.6%) former, and 3102 (70%) never smokers. During follow-up (median, 13.8 years), 254 participants developed CHD. After risk factor adjustment, CHD risk was significantly higher in current smokers compared with never smokers (HR, 2.11; 95% CI, 1.39-3.18); the difference between former smokers and never smokers (HR, 1.37; 95% CI, 1.0-1.90) did not achieve statistical significance. Among current smokers, we did not observe a dose-response effect for CHD risk. Additionally, in multivariable logistic regression models with a subset of our analytic cohort, current smokers had greater odds of coronary artery calcification score >0 compared with never smokers (odds ratio, 2.63; 95% CI, 1.88-3.68). Conclusions In a large prospective cohort of Black adults, current smoking was associated with a >2-fold increased risk of CHD over a median follow-up of greater than a decade.

Indexed as

Coronary Artery DiseaseVascular CalcificationBlack or African AmericanCigarette SmokingCoronary VesselsFemaleHeart Disease Risk FactorsHumansLongitudinal StudiesMaleMiddle AgedNon-SmokersRisk AssessmentSmokersUnited StatesBlack adultscigarette smokingcoronary artery calcificationcoronary heart diseaseJackson Heart Study

Identifiers

PMID33754833
PMCPMC8174312
OpenAlexW3138707380

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.