Evidence map›Paper›PMID 33754274›Full record

SynthesisEating and weight disorders : EWD2022

Brain networks in eating disorders: a systematic review of graph theory studies.

Enrico Collantoni, Francesco Alberti, Valentina Meregalli, Paolo Meneguzzo, Elena Tenconi, Angela Favaro

Abstract readSystematic Review
In one paragraph

Synthesis in Eating and weight disorders : EWD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Cortical complexity in eating disorders: a systematic review and qualitative synthesis.European archives of psychiatry and clinical neuroscience · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Enrico Collantoni *Department of Neurosciences, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy. enrico.collantoni@unipd.it.ORCID http://orcid.org/0000-0002-6730-1778
Francesco Alberti *Department of Neurosciences, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy.ORCID http://orcid.org/0000-0001-5732-8224
Valentina MeregalliDepartment of Neurosciences, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy.ORCID http://orcid.org/0000-0003-0016-1237
Paolo MeneguzzoDepartment of Neurosciences, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy.ORCID http://orcid.org/0000-0003-3323-6071
Elena TenconiDepartment of Neurosciences, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy.ORCID http://orcid.org/0000-0003-1629-9871
Angela FavaroDepartment of Neurosciences, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy.ORCID http://orcid.org/0000-0002-6540-5194

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecent evidence from neuroimaging research has shown that eating disorders (EDs) are characterized by alterations in interconnected neural systems, whose characteristics can be usefully described by connectomics tools. The present paper aimed to review the neuroimaging literature in EDs employing connectomic tools, and, specifically, graph theory analysis.

methodsA systematic review of the literature was conducted to identify studies employing graph theory analysis on patients with eating disorders published before the 22nd of June 2020.

resultsTwelve studies were included in the systematic review. Ten of them address anorexia nervosa (AN) (AN = 199; acute AN = 85, weight recovered AN with acute diagnosis = 24; fully recovered AN = 90). The remaining two articles address patients with bulimia nervosa (BN) (BN = 48). Global and regional unbalance in segregation and integration properties were described in both disorders. DISCUSSION: The literature concerning the use of connectomics tools in EDs evidenced the presence of alterations in the topological characteristics of brain networks at a global and at a regional level. Changes in local characteristics involve areas that have been demonstrated to be crucial in the neurobiology and pathophysiology of EDs. Regional imbalances in network properties seem to reflect on global patterns. LEVEL OF EVIDENCE: Level I, systematic review.

Indexed as

Anorexia NervosaBulimia NervosaFeeding and Eating DisordersBrainHumansAnorexia nervosaBrain networksBulimia nervosaEating disordersGraph theoryNeuroimaging

Identifiers

PMID33754274
PMCPMC8860943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.