Evidence map›Paper›PMID 33754254›Full record

ReviewAnnals of biomedical engineering2021

Mechanics of Uterosacral Ligaments: Current Knowledge, Existing Gaps, and Future Directions.

Kandace Donaldson, Alyssa Huntington, Raffaella De Vita

Abstract readReview
PubMed Publisher
In one paragraph

Review in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Transcriptomic analysis revealsZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. In-plane and out-of-plane deformations of gilt utero-sacral ligaments.Journal of the mechanical behavior of biomedical materials · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kandace Donaldson, 330A Kelly Hall, 325 Stanger Street, Blacksburg, VA, 24061, USA.
Alyssa Huntington, 330A Kelly Hall, 325 Stanger Street, Blacksburg, VA, 24061, USA.
Raffaella De Vita, 335 Kelly Hall, 325 Stanger Street, Blacksburg, VA, 24061, USA. devita@vt.edu.ORCID http://orcid.org/0000-0003-3157-9409
Virginia Tech · US

Funding

VT Initiative for Maximizing Student DiversityR25GM072767 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SMITH, EDWARD J · 2007 to 2021
$6.9M
NIGMS NIH HHS R25 GM072767
6 · The paper itself

Abstract

The uterosacral ligaments (USLs) are important anatomical structures that support the uterus and apical vagina within the pelvis. As these structures are over-stretched, become weak, and exhibit laxity, pelvic floor disorders such as pelvic organ prolapse occur. Although several surgical procedures to treat pelvic floor disorders are directed toward the USLs, there is still a lot that is unknown about their function. This manuscript presents a review of the current knowledge on the mechanical properties of the USLs. The anatomy, microstructure, and clinical significance of the USLs are first reviewed. Then, the results of published experimental studies on the in vivo and ex vivo, uniaxial and biaxial tensile tests are compiled. Based on the existing findings, research gaps are identified and future research directions are discussed. The purpose of this exhaustive review is to help new researchers navigate scientific literature on the mechanical properties of the USLs. The use of these structures remains very popular in reconstructive surgeries that restore and augment the support of pelvic organs, especially as synthetic surgical mesh implants continue to be highly controversial.

Indexed as

LigamentsPelvic Organ ProlapseSurgical MeshUterusVaginaAnimalsFemaleHumansMechanicsPelvic floor supportProlapseUterosacral ligaments

Identifiers

PMID33754254
OpenAlexW3137899055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.