Evidence map›Paper›PMID 33754069›Full record

ArticleTheranostics2021

The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer.

Zhongyuan Wang, Liang Zhou, Yejun Wang, Quanzhou Peng, Huan Li, Xin Zhang, Zijie Su, Jiaxing Song, Qi Sun, Sapna Sayed and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  9. mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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  13. R-spondin-1 induces Axin degradation via the LRP6-CK1ε axis.Cell communication and signaling : CCS · 2024
    Article
  14. Article
  15. Kindlin-2 controls angiogenesis through modulating Notch1 signaling.Cellular and molecular life sciences : CMLS · 2023
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Zhongyuan WangGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Liang ZhouGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Yejun WangDepartment of Physiology, School of Medicine, Health Science Center, Shenzhen University, Shenzhen 518060, China.
Quanzhou PengDepartment of Pathology, Shenzhen People's Hospital, the Second Clinical Medical College of Jinan University, Shenzhen 518020, China.
Huan LiGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Xin ZhangGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Zijie SuGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Jiaxing SongGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Qi SunGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Sapna SayedGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Shanshan LiuGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Desheng LuGuangdong Provincial Key Laboratory of Regional Immunity and Diseases, Cancer Research Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen 518055, China.
Shenzhen University Health Science Center · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarcinogenesisCasein Kinase 1 epsilonCasein Kinase IdeltaCell LineCell Line, TumorCell MovementCell ProliferationColorectal NeoplasmsCo-Repressor ProteinsDown-RegulationGene Expression Regulation, NeoplasticHCT116 CellsHEK293 CellsHumansOrganoidsPhosphorylationCasein Kinase 1 epsilonCasein Kinase IdeltaCo-Repressor ProteinsTLE5 protein, humanAESCK1δ/εcolorectal cancerSKP2Wnt/β-catenin signaling

Identifiers

PMID33754069
PMCPMC7977458
OpenAlexW3138512368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.