Evidence map›Paper›PMID 33754055›Full record

ArticleTheranostics2021

Redox-sensitive carrier-free nanoparticles self-assembled by disulfide-linked paclitaxel-tetramethylpyrazine conjugate for combination cancer chemotherapy.

Liang Zou, Xiaowei Liu, Jingjing Li, Wei Li, Lele Zhang, Chaomei Fu, Jinming Zhang, Zhongwei Gu

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Liang ZouKey Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural Affairs, Chengdu University, Chengdu 610106, People's Republic of China.
Xiaowei LiuSchool of Basic Medical Sciences, Chengdu University, Chengdu 610106, People's Republic of China.
Jingjing LiState Key Laboratory of Southwestern Chinese Medicine Resources, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People's Republic of China.
Wei LiSchool of Basic Medical Sciences, Chengdu University, Chengdu 610106, People's Republic of China.
Lele ZhangSchool of Basic Medical Sciences, Chengdu University, Chengdu 610106, People's Republic of China.
Chaomei FuState Key Laboratory of Southwestern Chinese Medicine Resources, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People's Republic of China.
Jinming ZhangState Key Laboratory of Southwestern Chinese Medicine Resources, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People's Republic of China.
Zhongwei GuCollege of Materials Science and Engineering, Nanjing Tech Universit`y, Nanjing 211816, People's Republic of China.
Chengdu University of Traditional Chinese Medicine · CNChengdu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiogenesis InhibitorsAnimalsAntineoplastic Combined Chemotherapy ProtocolsApoptosisCell Cycle CheckpointsCell LineCell Line, TumorDisulfidesDrug Delivery SystemsDrug LiberationFemaleHumansHuman Umbilical Vein Endothelial CellsMiceMice, Inbred BALB CMice, NudeAngiogenesis InhibitorsDisulfidesPaclitaxelPyrazinestetramethylpyrazineVascular Endothelial Growth Factor Receptor-2combination chemotherapydisulfide linkagedrug conjugatepaclitaxelself-assembly.tetramethylpyrazine

Identifiers

PMID33754055
PMCPMC7977472
OpenAlexW3198809545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.