Evidence map›Paper›PMID 33754016›Full record

ArticleTheranostics2021

The histone acetyltransferase HBO1 functions as a novel oncogenic gene in osteosarcoma.

Yan-Yang Gao, Zhuo-Yan Ling, Yun-Rong Zhu, Ce Shi, Yin Wang, Xiang-Yang Zhang, Zhi-Qing Zhang, Qin Jiang, Min-Bin Chen, Shuofei Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 75 citations in OpenAlex.

  1. Research progress on lysine acetylation (Review).International journal of molecular medicine · 2026
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Yan-Yang GaoDepartment of Pediatrics, Xinyi people's Hospital, Xinyi, China.
Zhuo-Yan LingDepartment of Orthopedics, the Second Affiliated Hospital of Soochow University, Suzhou, China.
Yun-Rong ZhuDepartment of Orthopedics, The Affiliated Jiangyin Hospital of Medical College of Southeast University, Jiangyin, China.
Ce ShiDepartment of Orthopedics, The Affiliated Suqian Hospital of Xuzhou Medical University, Suqian, China.
Yin WangJiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience, Soochow University, Suzhou, China.
Xiang-Yang ZhangDepartment of Orthopedics, the Second Affiliated Hospital of Soochow University, Suzhou, China.
Zhi-Qing ZhangJiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience, Soochow University, Suzhou, China.
Qin JiangThe Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Min-Bin ChenDepartment of Radiotherapy and Oncology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
Shuofei YangDepartment of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Cong CaoJiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience, Soochow University, Suzhou, China.
Soochow University · CNFirst People's Hospital of Kunshan · CNJiangyin People's Hospital · CNNanjing Medical University · CNRenji Hospital · CNSecond Affiliated Hospital of Nanjing Medical University · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HBO1 (KAT7 or MYST2) is a histone acetyltransferase that acetylates H3 and H4 histones.

Indexed as

AnimalsApoptosisBone NeoplasmsCell Line, TumorCell MovementCell ProliferationCell SurvivalCRISPR-Cas SystemsEnzyme InhibitorsFemaleGene Knockout TechniquesHistone AcetyltransferasesHumansMaleMiceMice, SCIDEnzyme InhibitorsHistone AcetyltransferasesKAT7 protein, humanRNA, MessengerRNA, Small InterferingTrans-ActivatorsZNF384 protein, humanHBO1histone acetylationosteosarcomaWM-3835

Identifiers

PMID33754016
PMCPMC7978299
OpenAlexW3138920594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.