Evidence map›Paper›PMID 33754014›Full record

ArticleTheranostics2021

Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation.

Zih-Chan Lin, Tsong-Long Hwang, Tse-Hung Huang, Kohei Tahara, Jiří Trousil, Jia-You Fang

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Metagenomics reveals unique gut mycobiome biomarkers in psoriasis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Zih-Chan LinGraduate Institute of Biomedical Sciences, Chang Gung University, Kweishan, Taoyuan, Taiwan.
Tsong-Long HwangGraduate Institute of Natural Products, Chang Gung University, Kweishan, Taoyuan, Taiwan.
Tse-Hung HuangResearch Center for Food and Cosmetic Safety and Research Center for Chinese Herbal Medicine, Chang Gung University of Science and Technology, Kweishan, Taoyuan, Taiwan.
Kohei TaharaLaboratory of Pharmaceutical Engineering, Gifu Pharmaceutical University, Gifu, Japan.
Jiří TrousilInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic.
Jia-You FangGraduate Institute of Natural Products, Chang Gung University, Kweishan, Taoyuan, Taiwan.
Chang Gung University · TWChang Gung Memorial Hospital · TWChang Gung University of Science and Technology · TWCzech Academy of Sciences, Institute of Macromolecular Chemistry · CZGifu Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To improve the treatment of psoriasiform inflammation, we developed actively targeted nanocarriers loaded with the phosphodiesterase 4 inhibitor AN2728.

Indexed as

NanoparticlesPhospholipidsPolylactic Acid-Polyglycolic Acid CopolymerAnimalsAntibodiesBoron CompoundsBridged Bicyclo Compounds, HeterocyclicChemokine CXCL1Chemokine CXCL2ChemotaxisDesmoglein 3Disease Models, AnimalDrug CarriersDrug Delivery SystemsEpidermisHaCaT CellsAntibodiesBoron CompoundsBridged Bicyclo Compounds, HeterocyclicChemokine CXCL1Chemokine CXCL2crisaboroleDesmoglein 3Drug CarriersImmunoconjugatesPhosphodiesterase 4 InhibitorsPhospholipidsPolylactic Acid-Polyglycolic Acid Copolymeractive targetingdesmoglein 3keratinocytelipid-polymer nanohybridmonovalent antibodypsoriasis

Identifiers

PMID33754014
PMCPMC7978323
OpenAlexW3136910921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.