Evidence map›Paper›PMID 33753982›Full record

ArticleNano today2021

2D MXenes with antiviral and immunomodulatory properties: A pilot study against SARS-CoV-2.

Mehmet Altay Unal, Fatma Bayrakdar, Laura Fusco, Omur Besbinar, Christopher E Shuck, Süleyman Yalcin, Mine Turktas Erken, Aykut Ozkul, Cansu Gurcan, Oguzhan Panatli and 16 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 124 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Periodic Table of Immunomodulatory Elements and Derived Two-Dimensional Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  14. Article
  15. The NbInternational journal of nanomedicine · 2025
    Article
  16. Article
  17. Comprehensive synthesis of TiNature protocols · 2024
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 9 institutions in 4 countries.

Mehmet Altay UnalStem Cell Institute, Ankara University, Balgat, Ankara, Turkey.
Fatma BayrakdarMinistry of Health General Directorate of Public Health, Microbiology References Laboratory, Ankara, Turkey.
Laura FuscoDepartment of Biomedical Sciences, University of Padua, Padua, Italy.
Omur BesbinarStem Cell Institute, Ankara University, Balgat, Ankara, Turkey.
Christopher E ShuckA.J. Drexel Nanomaterials Institute and Department of Materials Science and Engineering, Drexel University, Philadelphia, PA, USA.
Süleyman YalcinMinistry of Health General Directorate of Public Health, Microbiology References Laboratory, Ankara, Turkey.
Mine Turktas ErkenDepartment of Biology, Gazi University, Ankara, Turkey.
Aykut OzkulDepartment of Virology, Faculty of Veterinary Medicine, Ankara University, Ankara, Turkey.
Cansu GurcanStem Cell Institute, Ankara University, Balgat, Ankara, Turkey.
Oguzhan PanatliDepartment of Biomedical Engineering, Ankara University, Golbasi, Ankara, Turkey.
Gokce Yagmur SummakStem Cell Institute, Ankara University, Balgat, Ankara, Turkey.
Cemile GokceDepartment of Biomedical Engineering, Ankara University, Golbasi, Ankara, Turkey.
Marco OrecchioniLa Jolla Institute for Immunology, La Jolla, CA, USA.
Arianna GazziDepartment of Biomedical Sciences, University of Padua, Padua, Italy.
Flavia VitaleDepartment of Neurology, Bioengineering, Physical Medicine & Rehabilitation, Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.
Julia SomersOregon Health & Sciences University, Department of Molecular and Medical Genetics, Portland, OR, USA.
Emek DemirOregon Health & Sciences University, Department of Molecular and Medical Genetics, Portland, OR, USA.
Serap Suzuk YildizMinistry of Health General Directorate of Public Health, Microbiology References Laboratory, Ankara, Turkey.
Hasan NazirDepartment of Chemistry, Ankara University, Tandogan, Ankara, Turkey.
Jean-Charles GrivelDeep Phenotyping Core, Sidra Medicine, Doha, Qatar.
Davide BedognettiCancer Research Department, Sidra Medicine, Doha, Qatar.
Andrea CrisantiDepartment of Molecular Medicine, Padua University Hospital, Padua, Italy.
Kamil Can AkcaliStem Cell Institute, Ankara University, Balgat, Ankara, Turkey.
Yury GogotsiA.J. Drexel Nanomaterials Institute and Department of Materials Science and Engineering, Drexel University, Philadelphia, PA, USA.
Lucia Gemma DeloguDepartment of Biomedical Sciences, University of Padua, Padua, Italy.
Açelya YilmazerStem Cell Institute, Ankara University, Balgat, Ankara, Turkey.
Ankara University · TRUniversity of Padua · ITMinistry of Health · TRDrexel University · USOregon Health & Science University · USGazi University · TRHamad bin Khalifa University · QALa Jolla Institute for Immunology · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two-dimensional transition metal carbides/carbonitrides known as MXenes are rapidly growing as multimodal nanoplatforms in biomedicine. Here, taking SARS-CoV-2 as a model, we explored the antiviral properties and immune-profile of a large panel of four highly stable and well-characterized MXenes - Ti

Indexed as

Antiviral propertiesImmune systemMXeneNanomedicineSingle cell mass cytometryToxicityViral clades

Identifiers

PMID33753982
PMCPMC7969865
OpenAlexW3138505212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.