Evidence map›Paper›PMID 33753914›Full record

ArticleEuropean journal of human genetics : EJHG2021

The Ami and Yami aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations.

Kai Tätte, Ene Metspalu, Helen Post, Leire Palencia-Madrid, Javier Rodríguez Luis, Maere Reidla, Anneliis Rea, Erika Tamm, Everett J Moding, Marian M de Pancorbo and 3 more

Abstract read
In one paragraph

Article in European journal of human genetics : EJHG, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kai TätteEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Ene MetspaluEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Helen PostEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Leire Palencia-MadridBIOMICs Research Group, Lascaray Research Center, University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain.ORCID 0000-0002-4351-3450
Javier Rodríguez LuisArea de Antropología, Facultad de Biología, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.ORCID 0000-0002-1145-2585
Maere ReidlaEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Anneliis ReaDepartment of Evolutionary Biology, Institute of Cell and Molecular Biology, University of Tartu, Tartu, Estonia.
Erika TammEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Everett J ModingDepartment of Radiation Oncology, Stanford University Medical Center, Stanford, CA, USA.ORCID 0000-0001-7913-5351
Marian M de PancorboBIOMICs Research Group, Lascaray Research Center, University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain.
Ralph Garcia-BertrandDepartment of Molecular Biology, Colorado College, Colorado Springs, CO, USA.
Mait MetspaluEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Rene J HerreraDepartment of Molecular Biology, Colorado College, Colorado Springs, CO, USA. renejustoherrera@gmail.com.ORCID 0000-0002-5119-4381

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article reports on the genetic characteristics of the Ami and Yami, two aboriginal populations of Taiwan. Y-SNP and mtDNA markers as well as autosomal SNPs were utilized to investigate the phylogenetic relationships to groups from MSEA (mainland Southeast Asia), ISEA (island Southeast Asia), and Oceania. Both the Ami and Yami have limited genetic diversity, with the Yami having even less diversity than the Ami. The partitioning of populations within the PCA plots based on autosomal SNPs, the profile constitution observed in the structure analyses demonstrating similar composition among specific populations, the average IBD (identical by descent) tract length gradients, the average total length of genome share among the populations, and the outgroup f3 results all indicate genetic affinities among populations that trace a geographical arc from Taiwan south into the Philippine Archipelago, Borneo, Indonesia, and Melanesia. Conversely, a more distant kinship between the Ami/Yami and MSEA based on all the markers examined, the total mtDNA sequences as well as the admixture f3 and f4 analyses argue against strong genetic contribution from MSEA to the Austronesian dispersal. The sharing of long IBD tracts, total genome length, and the large number of segments in common between the Ami/Yami and the Society Archipelago populations East Polynesia standout considering they are located about 10,700 km apart.

Indexed as

Genetics, PopulationAsia, EasternAsian PeopleChromosomes, Human, YDNA, MitochondrialGenotypeHaplotypesHumansPacific IslandsPhylogenyPhylogeographyPolymorphism, Single NucleotideTaiwanDNA, Mitochondrial

Identifiers

PMID33753914
PMCPMC8298601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.