ArticleNature ecology & evolution2021
Widespread Denisovan ancestry in Island Southeast Asia but no evidence of substantial super-archaic hominin admixture.
Article in Nature ecology & evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Scalable ARG-free Detection of Denisovan-mediated Superarchaic Introgression Reveals Heterogeneous Patterns across Populations.bioRxiv : the preprint server for biology · 2026Article
- Homo luzonensis and the role of homoplasy in the morphology of hominin insular species.Cladistics : the international journal of the Willi Hennig Society · 2026Article
- Recent advances in methods to characterize archaic introgression in modern humans.Genome research · 2026Review
- A Late Pleistocene archaic human tooth from Gua Dagang (Trader's Cave), Niah national park, Sarawak (Malaysia).PloS one · 2025Article
- The genetic origins and impacts of historical Papuan migrations into Wallacea.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Computational Genomics and Its Applications to Anthropological Questions.American journal of biological anthropology · 2024Review
- Review
- Denisovan and Neanderthal archaic introgression differentially impacted the genetics of complex traits in modern populations.BMC biology · 2022Article
- A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos.Nature communications · 2022Article
- Fossils, fish and tropical forests: prehistoric human adaptations on the island frontiers of Oceania.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Unveiling the Genetic History of the Maniq, a Primary Hunter-Gatherer Society.Genome biology and evolution · 2022Article
- Underrepresented Populations at the Archaic Introgression Frontier.Frontiers in genetics · 2022Article
- Evolutionary genetics and acclimatization in nephrology.Nature reviews. Nephrology · 2021Review
- Philippine Ayta possess the highest level of Denisovan ancestry in the world.Current biology : CB · 2021Article
- Article
- Our Tangled Family Tree: New Genomic Methods Offer Insight into the Legacy of Archaic Admixture.Genome biology and evolution · 2021Review
- Article
- Introgressive Hybridization and Hypoxia Adaptation in High-Altitude Vertebrates.Frontiers in genetics · 2021Review
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12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hominin fossil record of Island Southeast Asia (ISEA) indicates that at least two endemic 'super-archaic' species-Homo luzonensis and H. floresiensis-were present around the time anatomically modern humans arrived in the region >50,000 years ago. Intriguingly, contemporary human populations across ISEA carry distinct genomic traces of ancient interbreeding events with Denisovans-a separate hominin lineage that currently lacks a fossil record in ISEA. To query this apparent disparity between fossil and genetic evidence, we performed a comprehensive search for super-archaic introgression in >400 modern human genomes, including >200 from ISEA. Our results corroborate widespread Denisovan ancestry in ISEA populations, but fail to detect any substantial super-archaic admixture signals compatible with the endemic fossil record of ISEA. We discuss the implications of our findings for the understanding of hominin history in ISEA, including future research directions that might help to unlock more details about the prehistory of the enigmatic Denisovans.
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