ArticleScientific reports2021
Optical signatures of radiofrequency ablation in biological tissues.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Integrated device for optoacoustically-guided ultrasound surgery.Nature communications · 2026Article
- Temperature-induced hemoglobin dynamics: oxygenation-dependent evolution of hemoglobin spectral response in the near-infrared.Biophotonics discovery · 2026Article
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- Impact of catheter ablation for ventricular tachycardia on left ventricular ejection fraction in patients with structural heart disease.Journal of arrhythmia · 2025Article
- Towards molecular imaging-guided intervention theatres in oncology.European journal of nuclear medicine and molecular imaging · 2024Article
- Optical coherence tomography for the detection of electrothermal ureteral injury in anBiophotonics discovery · 2024Article
- Optical signatures of thermal damage on ex-vivo brain, lung and heart tissues using time-domain diffuse optical spectroscopy.Biomedical optics express · 2024Article
- Evaluating the efficacy of Nd:YAG fourth harmonic (266 nm) in comparison with ArF excimer (193 nm) in laser corneal reshaping: ex vivo pilot study.International ophthalmology · 2023Article
- High-contrast spectroscopic photoacoustic characterization of thermal tissue ablation in the visible spectrum.Ultrasonography (Seoul, Korea) · 2023Article
- Photoacoustic imaging for characterization of radiofrequency ablated cardiac tissues.Lasers in medical science · 2023Review
- Optical Study of Lysozyme Molecules in Aqueous Solutions after Exposure to Laser-Induced Breakdown.Biomolecules · 2022Article
- Estimation of porcine pancreas optical properties in the 600-1100 nm wavelength range for light-based therapies.Scientific reports · 2022Article
- Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise.Journal of biomedical optics · 2022Article
- Estimating optical parameters of biological tissues with photon-counting micro-CT.Journal of the Optical Society of America. A, Optics, image science, and vision · 2022Article
- Nanoparticle-Mediated Photothermal Therapy Limitation in Clinical Applications Regarding Pain Management.Nanomaterials (Basel, Switzerland) · 2022Review
- Quantification of irrigated lesion morphology using near-infrared spectroscopy.Scientific reports · 2021Article
- Annular Fiber Probe for Interstitial Illumination in Photoacoustic Guidance of Radiofrequency Ablation.Sensors (Basel, Switzerland) · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate monitoring of treatment is crucial in minimally-invasive radiofrequency ablation in oncology and cardiovascular disease. We investigated alterations in optical properties of ex-vivo bovine tissues of the liver, heart, muscle, and brain, undergoing the treatment. Time-domain diffuse optical spectroscopy was used, which enabled us to disentangle and quantify absorption and reduced scattering spectra. In addition to the well-known global (1) decrease in absorption, and (2) increase in reduced scattering, we uncovered new features based on sensitive detection of spectral changes. These absorption spectrum features are: (3) emergence of a peak around 840 nm, (4) redshift of the 760 nm deoxyhemoglobin peak, and (5) blueshift of the 970 nm water peak. Treatment temperatures above 100 °C led to (6) increased absorption at shorter wavelengths, and (7) further decrease in reduced scattering. This optical behavior provides new insights into tissue response to thermal treatment and sets the stage for optical monitoring of radiofrequency ablation.
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