ArticleMolecular cancer research : MCR2021
Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor.
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Article in Molecular cancer research : MCR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 38 citations in OpenAlex.
- Review
- Multi-layered molecular profiling informs the diagnosis and targeted therapy of desmoplastic small round cell tumor.Nature communications · 2026Article
- Harnessing AACR Project GENIE to Define the Molecular Features of Desmoplastic Small Round Cell Tumor.Current issues in molecular biology · 2026Article
- Review
- Spectrum and Clinical Impact of Secondary Genetic Alterations in Translocation-Associated Sarcomas.JCO precision oncology · 2025Article
- Replication Stress Is an Actionable Genetic Vulnerability in Desmoplastic Small Round Cell Tumors.Cancer research · 2025Article
- DNMT3A facilitates breast cancer progression via regulating ADAMTS8 mediated EGFR-MEK-ERK activation.PloS one · 2025Article
- Review
- HER2 Antibody-Drug Conjugates Are Active against Desmoplastic Small Round Cell Tumor.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024Article
- EWS-WT1 fusion isoforms establish oncogenic programs and therapeutic vulnerabilities in desmoplastic small round cell tumors.Nature communications · 2024Article
- Xenografting Human Musculoskeletal Sarcomas in Mice, Chick Embryo, and Zebrafish: How to Boost Translational Research.Biomedicines · 2024Review
- Single-cell multiomics profiling reveals heterogeneous transcriptional programs and microenvironment in DSRCTs.Cell reports. Medicine · 2024Article
- Chromoplexy Is a Frequent Early Clonal Event in EWSR1-Rearranged Round Cell Sarcomas That Can Be Detected Using Clinically Validated Targeted Sequencing Panels.Cancer research · 2024Article
- Comprehensive Transcriptomic Analysis of EWSR1::WT1 Targets Identifies CDK4/6 Inhibitors as an Effective Therapy for Desmoplastic Small Round Cell Tumors.Cancer research · 2024Article
- Desmoplastic small round cell tumor: from genomics to targets, potential paths to future therapeutics.Frontiers in cell and developmental biology · 2024Review
- Article
- Effectiveness of irinotecan plus trabectedin on a desmoplastic small round cell tumor patient-derived xenograft.Disease models & mechanisms · 2023Article
- Genomic Breakpoint Characterization and Transcriptome Analysis of Metastatic, Recurrent Desmoplastic Small Round Cell Tumor.Sarcoma · 2023Article
- Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma.British journal of cancer · 2022Article
- Small round cell sarcomas.Nature reviews. Disease primers · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 1 institution in 1 country.
Emily K Slotkin *Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York. slotkine@mskcc.org.ORCID 0000-0002-4463-5759
Anita S Bowman *Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-8651-5317
Max F LevineDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Filemon Dela CruzDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Diego F CoutinhoDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Glorymar I SanchezDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Nestor RosalesDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Shakeel ModakDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
William D TapDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-7779-2796
Mrinal M GounderDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Katherine A ThorntonDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Nancy BouvierDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Daoqi YouDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Gunes GundemDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Justin T GerstleDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Todd E HeatonDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0003-3515-0028
Michael P LaQuagliaDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0002-7059-9851
Leonard H WexlerDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Paul A MeyersDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-6146-6101
Andrew L KungDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Elli PapaemmanuilDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Ahmet Zehir *Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-5406-4104
Marc Ladanyi *Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Neerav Shukla *Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.
Memorial Sloan Kettering Cancer Center · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MTargeting Oncogenic Pathways in Genetically Complex SarcomasP50CA217694 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI William D. Tap · 2018 to 2026
$21.5MNCI NIH HHS P30 CA008748NCI NIH HHS P50 CA217694
Abstract
Desmoplastic small round cell tumor (DSRCT) is characterized by the
Indexed as
Gene Expression Regulation, NeoplasticAdolescentAdultCell Line, TumorChildDesmoplastic Small Round Cell TumorDNA Copy Number VariationsFemaleGene Expression ProfilingHigh-Throughput Nucleotide SequencingHumansMaleMiddle AgedMultiplex Polymerase Chain ReactionOncogene Proteins, FusionReceptor, Fibroblast Growth Factor, Type 4EWSR1 protein, humanFGFR4 protein, humanOncogene Proteins, FusionReceptor, Fibroblast Growth Factor, Type 4RNA-Binding Protein EWSWT1 protein, humanWT1 Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.