ArticleProceedings of the National Academy of Sciences of the United States of America2021
Shape anisotropy-governed locomotion of surface microrollers on vessel-like microtopographies against physiological flows.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Article
- Unlocking miniature brilliance: micro/nanorobots for advanced dental theranostics.Journal of nanobiotechnology · 2026Review
- Hybrid magnetic-electric actuation for enhanced motion control and multi-surface operation of Janus microrobots.Nature communications · 2026Article
- Blood Cell-Based Drug Delivery Systems: From Biological and Mechanical Design to Clinical Applications.Bioengineering (Basel, Switzerland) · 2026Review
- Observation of a backward sliding motion for rollers on surfaces in viscoelastic fluid.Nature communications · 2026Article
- Biohybrid Microrobots Based on Jellyfish Stinging Capsules and Janus Particles for In Vitro Deep-Tissue Drug Penetration.Small science · 2025Article
- Rolling vesicles: From confined rotational flows to surface-enabled motion.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Surface motion dynamics and swimming control of planar magnetic microswimmers.Scientific reports · 2025Article
- Robotic Microcapsule Assemblies with Adaptive Mobility for Targeted Treatment of Rugged Biological Microenvironments.ACS nano · 2025Article
- Microrobotic Swarms for Cancer Therapy.Research (Washington, D.C.) · 2025Review
- Spatially selective delivery of living magnetic microrobots through torque-focusing.Nature communications · 2024Article
- Article
- Inductive sensing of magnetic microrobots under actuation by rotating magnetic fields.PNAS nexus · 2023Article
- The mismatch between experimental and computational fluid dynamics analyses for magnetic surface microrollers.Scientific reports · 2023Article
- Rolling of soft microbots with tunable traction.Science advances · 2023Article
- Magnetically boosted 1D photoactive microswarm for COVID-19 face mask disruption.Nature communications · 2023Article
- Achieving Control in Micro-/Nanomotor Mobility.Angewandte Chemie (International ed. in English) · 2023Review
- Reconfigurable Vortex-like Paramagnetic Nanoparticle Swarm with Upstream Motility and High Body-length Ratio Velocity.Research (Washington, D.C.) · 2023Article
- System integration of magnetic medical microrobots: from design to control.Frontiers in robotics and AI · 2023Review
- Rolling microswarms along acoustic virtual walls.Nature communications · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Surface microrollers are promising microrobotic systems for controlled navigation in the circulatory system thanks to their fast speeds and decreased flow velocities at the vessel walls. While surface propulsion on the vessel walls helps minimize the effect of strong fluidic forces, three-dimensional (3D) surface microtopography, comparable to the size scale of a microrobot, due to cellular morphology and organization emerges as a major challenge. Here, we show that microroller shape anisotropy determines the surface locomotion capability of microrollers on vessel-like 3D surface microtopographies against physiological flow conditions. The isotropic (single, 8.5 µm diameter spherical particle) and anisotropic (doublet, two 4 µm diameter spherical particle chain) magnetic microrollers generated similar translational velocities on flat surfaces, whereas the isotropic microrollers failed to translate on most of the 3D-printed vessel-like microtopographies. The computational fluid dynamics analyses revealed larger flow fields generated around isotropic microrollers causing larger resistive forces near the microtopographies, in comparison to anisotropic microrollers, and impairing their translation. The superior surface-rolling capability of the anisotropic doublet microrollers on microtopographical surfaces against the fluid flow was further validated in a vessel-on-a-chip system mimicking microvasculature. The findings reported here establish the design principles of surface microrollers for robust locomotion on vessel walls against physiological flows.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.