Observational studyProceedings of the National Academy of Sciences of the United States of America2021
Cingulo-opercular control network and disused motor circuits joined in standby mode.
Observational study in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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Who cites it
30 citing papers in PubMed.
- Spatial and Functional Organization of the Somato-Cognitive Action Network During Cue and Execution of Motor Tasks.Research square · 2026Article
- Large-scale neural network compensation associated with camouflaging in trait autism and its potential mental health costs.Molecular autism · 2026Article
- Different Brain Network Connectomic Relationships Subserve Hand Dexterity During Task Versus Resting States in People with Brain Tumors.Brain and behavior · 2025Article
- Connectome-based predictive modeling of handwriting and reading using task-evoked and resting-state functional connectivity.iScience · 2025Article
- A dynamic framework of brain functional patterns shaped by spontaneous thoughts beyond the default mode network.Scientific reports · 2025Article
- Action-mode subnetworks for decision-making, action control, and feedback.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Disuse-driven plasticity in the human thalamus and putamen.Cell reports · 2025Article
- The human brainstem's red nucleus was upgraded to support goal-directed action.Nature communications · 2025Article
- Functional Neuroanatomy of Tics: A Brain Network Perspective.The Psychiatric clinics of North America · 2025Review
- Brain connectivity moderated the effects of cognitive intraindividual variability on mobility in cognitively frail older adults.Frontiers in aging neuroscience · 2025Article
- Prenatal social disadvantage is associated with alterations in functional networks at birth.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Measuring neuroplasticity in human development: the potential to inform the type and timing of mental health interventions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Predicting post-surgical functional status in high-grade glioma with resting state fMRI and machine learning.Journal of neuro-oncology · 2024Article
- Disuse-driven plasticity in the human thalamus and putamen.bioRxiv : the preprint server for biology · 2024Article
- The unity and diversity of verbal and visuospatial creativity: Dynamic changes in hemispheric lateralisation.Human brain mapping · 2023Article
- Thalamo-cortical and cerebello-cortical functional connectivity in development.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Resting-state cortical hubs in youth organize into four categories.Cell reports · 2023Article
- Differentiation between fetal and postnatal iron deficiency in altering brain substrates of cognitive control in pre-adolescence.BMC medicine · 2023Article
- Article
- Maturation of large-scale brain systems over the first month of life.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
Corrections and comments
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Authors and funding
23 authors.
Funding
Abstract
Whole-brain resting-state functional MRI (rs-fMRI) during 2 wk of upper-limb casting revealed that disused motor regions became more strongly connected to the cingulo-opercular network (CON), an executive control network that includes regions of the dorsal anterior cingulate cortex (dACC) and insula. Disuse-driven increases in functional connectivity (FC) were specific to the CON and somatomotor networks and did not involve any other networks, such as the salience, frontoparietal, or default mode networks. Censoring and modeling analyses showed that FC increases during casting were mediated by large, spontaneous activity pulses that appeared in the disused motor regions and CON control regions. During limb constraint, disused motor circuits appear to enter a standby mode characterized by spontaneous activity pulses and strengthened connectivity to CON executive control regions.
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