Evidence map›Paper›PMID 33753477›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

DNA affinity purification sequencing and transcriptional profiling reveal new aspects of nitrogen regulation in a filamentous fungus.

Lori B Huberman, Vincent W Wu, David J Kowbel, Juna Lee, Chris Daum, Igor V Grigoriev, Ronan C O'Malley, N Louise Glass

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Journal of fungi (Basel, Switzerland) · 2025
    Article
  6. Remodeling of perturbed chromatin can initiate de novo transcriptional and post-transcriptional silencing.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Article
  9. Regulation of nutrient utilization in filamentous fungi.Applied microbiology and biotechnology · 2023
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lori B HubermanPlant and Microbial Biology Department, University of California, Berkeley, CA 94720; huberman@cornell.edu Lglass@berkeley.edu.ORCID 0000-0003-2638-8528
Vincent W WuPlant and Microbial Biology Department, University of California, Berkeley, CA 94720.ORCID 0000-0001-9973-2508
David J KowbelPlant and Microbial Biology Department, University of California, Berkeley, CA 94720.ORCID 0000-0003-3985-8576
Juna LeeUS Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
Chris DaumUS Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0003-3895-5892
Igor V GrigorievPlant and Microbial Biology Department, University of California, Berkeley, CA 94720.ORCID 0000-0002-3136-8903
Ronan C O'MalleyUS Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0002-4907-0339
N Louise GlassPlant and Microbial Biology Department, University of California, Berkeley, CA 94720; huberman@cornell.edu Lglass@berkeley.edu.ORCID 0000-0002-4844-2890
Lawrence Berkeley National Laboratory · USEnergy Biosciences Institute · USUniversity of California, Berkeley · US

Funding

POSTGRADUATE TRAINING PROGRAM IN GENETICST32GM007127 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI DILLIN, ANDREW G · 1985 to 2016
$7.9M
NIGMS NIH HHS T32 GM007127
6 · The paper itself

Abstract

Sensing available nutrients and efficiently utilizing them is a challenge common to all organisms. The model filamentous fungus

Indexed as

Gene Expression Regulation, FungalCatabolite RepressionDNA-Binding ProteinsFungal ProteinsGene Regulatory NetworksMetabolic Networks and PathwaysNeurospora crassaNitrogenRNA-SeqTrans-ActivatorsTranscription FactorsDNA-Binding ProteinsFungal ProteinsNIT2 protein, Neurospora crassaNIT-4 protein, Neurospora crassaNitrogenTrans-ActivatorsTranscription FactorsDAPseqnitrogen utilizationnutrient sensingRNAseqtranscriptional networks

Identifiers

PMID33753477
PMCPMC8020665
OpenAlexW3136389878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.