Evidence map›Paper›PMID 33753463›Full record

ArticleMolecular and cellular biology2021

Long Noncoding RNA LINC01006 Facilitates Cell Proliferation, Migration, and Epithelial-Mesenchymal Transition in Lung Adenocarcinoma via Targeting the MicroRNA 129-2-3p/CTNNB1 Axis and Activating Wnt/β-Catenin Signaling Pathway.

Yu Zhang, Hailin Liu, Qiang Zhang, Zhenfa Zhang

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yu ZhangDepartment of Lung Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.
Hailin LiuDepartment of Lung Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.
Qiang ZhangDepartment of Lung Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.
Zhenfa ZhangDepartment of Lung Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.
Tianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung adenocarcinoma (LUAD) is a common type of malignancy of lung cancers. Long intergenic noncoding RNAs (lincRNAs) have emerged as crucial regulators of various cancers, including LUAD. LINC01006 is a newly discovered long noncoding RNA (lncRNA) whose function in LUAD remains to be explored. This study is to explore the role of LINC01006 in LUAD. Quantitative real-time PCR (RT-qPCR) analysis and Western blotting were used to determine the expression levels and protein levels, respectively. Functional assays and animal experiments investigated the role of LINC01006 both

Indexed as

AdenocarcinomaAnimalsbeta CateninCell Line, TumorCell MovementCell ProliferationDown-RegulationEpithelial-Mesenchymal TransitionHumansLung NeoplasmsMiceMice, NudeMicroRNAsRNA, Long NoncodingWnt Signaling Pathwaybeta CateninCTNNB1 protein, humanMicroRNAsMirn129 microRNA, humanRNA, Long NoncodingCTNNB1LINC01006LUADmiR-129-2-3pWnt/β-catenin pathway

Identifiers

PMID33753463
PMCPMC8316148
OpenAlexW3139180576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.