Evidence map›Paper›PMID 33753334›Full record

ArticleAntimicrobial agents and chemotherapy2021

Marvin J Núñez, Morena L Martínez, Atteneri López-Arencibia, Carlos J Bethencourt-Estrella, Desirée San Nicolás-Hernández, Ignacio A Jiménez, Jacob Lorenzo-Morales, José E Piñero, Isabel L Bazzocchi

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Diels-Alder Adducts fromInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Bioprospecting for Anti-Kinetoplastid Drug Discovery fromInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Marvin J NúñezLaboratorio de Investigación en Productos Naturales, Facultad de Química y Farmacia, Universidad de El Salvador, San Salvador, El Salvador.
Morena L MartínezLaboratorio de Investigación en Productos Naturales, Facultad de Química y Farmacia, Universidad de El Salvador, San Salvador, El Salvador.
Atteneri López-ArencibiaInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Departamento de Obstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, La Laguna, Tenerife, Canary Islands, Spain.
Carlos J Bethencourt-EstrellaInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Departamento de Obstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, La Laguna, Tenerife, Canary Islands, Spain.
Desirée San Nicolás-HernándezInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Departamento de Obstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, La Laguna, Tenerife, Canary Islands, Spain.
Ignacio A JiménezInstituto Universitario de Bio-Orgánica Antonio González, Departamento de Química Orgánica, Universidad de La Laguna, La Laguna, Tenerife, Canary Islands, Spain.
Jacob Lorenzo-MoralesInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Departamento de Obstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, La Laguna, Tenerife, Canary Islands, Spain.
José E PiñeroInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Departamento de Obstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, La Laguna, Tenerife, Canary Islands, Spain jpinero@ull.edu.es ilopez@ull.edu.es.ORCID 0000-0001-6233-8224
Isabel L BazzocchiInstituto Universitario de Bio-Orgánica Antonio González, Departamento de Química Orgánica, Universidad de La Laguna, La Laguna, Tenerife, Canary Islands, Spain jpinero@ull.edu.es ilopez@ull.edu.es.ORCID 0000-0002-7698-2704
Universidad de La Laguna · ESUniversity of El Salvador · SV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmaniasis and Chagas are among the most significant neglected tropical diseases. Due to several drawbacks with the current chemotherapy, developing new antikinetoplastid drugs has become an urgent issue. In the present work, a bioassay-guided investigation of the root bark of

Indexed as

Antiprotozoal AgentsLeishmania mexicanaLeishmaniasisMaytenusTrypanosoma cruziAnimalsMiceAntiprotozoal Agentsbioactive natural productsChagas diseaseleishmaniasis

Identifiers

PMID33753334
PMCPMC8316137
OpenAlexW3138498668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.