Evidence map›Paper›PMID 33752957›Full record

ArticleTrends in biochemical sciences2021

Resurrected Ancestors Reveal Origins of Metamorphism in XCL1.

Patricia J LiWang, Lee-Ping Wang, Andy LiWang

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in biochemical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Patricia J LiWangDepartment of Molecular and Cell Biology, University of California, Merced, CA 95343, USA. Electronic address: pliwang@ucmerced.edu.
Lee-Ping WangDepartment of Chemistry, University of California, Davis, CA 95616, USA. Electronic address: leeping@ucdavis.edu.
Andy LiWangDepartment of Chemistry and Biochemistry, University of California, Merced, CA 95343, USA. Electronic address: aliwang@ucmerced.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a recent study, Dishman et al. resurrected ancestors of the metamorphic chemokine, XCL1, inferred through phylogenetics, and found that metamorphism arose in the XCL1 lineage ~150 million years ago. A zigzagging evolutionary path suggests that the metamorphic properties are adaptive and reveals three design principles that could be used for technological applications.

Indexed as

Chemokines, CChemokines, Cchemokinelymphotactinmetamorphic, monomorphicNMRproteinXCL1

Identifiers

PMID33752957

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.