ReviewCritical care clinics2021
The Role of Renal Functional Reserve in Predicting Acute Kidney Injury.
Review in Critical care clinics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Risk factors for acute kidney injury after pediatric cardiac surgery: a meta-analysis.Pediatric nephrology (Berlin, Germany) · 2022Pooled it
- Low-energy cooling strategies modulate biomarkers of kidney injury risk in older adults exposed to very hot and dry heat.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Trial
- Heterogeneous effects of preoperative beta blockers on 30-day mortality after coronary artery bypass surgery.Annals of medicine · 2026Article
- Atypical Hemolytic Uremic Syndrome in Children and Adults With the Hot Spot C3 Gene Variant p.Arg161Trp.Kidney international reports · 2026Article
- Aberrant activation of renal functional reserve and reduced tubule flow, but not obstruction, is associated with cystogenesis inFunction (Oxford, England) · 2026Article
- Renal consequences of complex abdominal wall reconstruction.Hernia : the journal of hernias and abdominal wall surgery · 2026Review
- Discovery of a resistant cohort to acute kidney injury: insights from patients with septic shock.Critical care (London, England) · 2025Article
- From past to present to future: Terlipressin and hepatorenal syndrome-acute kidney injury.Hepatology (Baltimore, Md.) · 2025Review
- Framework for Kidney Health Follow-Up Among Neonates With Critical Cardiac Disease: A Report From the Neonatal Kidney Health Consensus Workshop.Journal of the American Heart Association · 2025Review
- The promise of biomarkers: precision medicine will pave a roadmap for pediatric acute kidney injury management in critically ill children.Intensive care medicine. Paediatric and neonatal · 2025Review
- Perioperative Acute Kidney Injury and Prognosis of Infants With Down Syndrome and Congenital Heart Disease.Cureus · 2024Article
- Chronic Kidney Disease Progression-A Challenge.Biomedicines · 2024Review
- Assessment of Risk Factors for Acute Kidney Injury with Machine Learning Tools in Children Undergoing Hematopoietic Stem Cell Transplantation.Journal of clinical medicine · 2024Article
- Article
- Hemodynamic Renal Reserve Response in Conscious Normotensive and Hypertensive Mice.Kidney & blood pressure research · 2024Article
- LC-MS/MS-Based Serum Metabolomics and Transcriptome Analyses for the Mechanism of Augmented Renal Clearance.International journal of molecular sciences · 2023Article
- Relationship between piperacillin concentrations, clinical factors and piperacillin/tazobactam-associated acute kidney injury.The Journal of antimicrobial chemotherapy · 2023Article
- Current Concepts of Pediatric Acute Kidney Injury-Are We Ready to Translate Them into Everyday Practice?Journal of clinical medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Renal functional reserve (RFR) is described as the difference between a glomerular filtration rate (GFR) measured at baseline and after protein stimulation. The percent change in GFR after a protein load varies based on differences in experimental conditions, with the use of an oral meat protein stimulus and a creatinine clearance method to quantify GFR showing the greatest RFR. A decline in RFR has been found in numerous patient groups. Recent investigations have suggested that a lower RFR may be associated with an increased risk of acute kidney injury and eventual chronic kidney disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.