Evidence map›Paper›PMID 33752726›Full record

ArticleThyroid research2021

Association between thyroid autoimmunity and ovarian reserve in women with hypothyroidism.

Felipe A Morales-Martínez, Luis H Sordia-Hernández, Martha Merino Ruiz, Selene Garcia-Luna, Otto H Valdés-Martínez, Oscar Vidal-Gutierez

Open access · goldAbstract read
In one paragraph

Article in Thyroid research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Felipe A Morales-MartínezCentro Universitario de Medicina Reproductiva, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León. Monterrey, Edificio Rodrigo Barragán 3er piso Ave., Av. Francisco I. Madero s/n y Gonzalitos Col. Mitras Centro, NL, C.P. 64460, Monterrey, Mexico. felipe.moralesm@uanl.mx.
Luis H Sordia-HernándezCentro Universitario de Medicina Reproductiva, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León. Monterrey, Edificio Rodrigo Barragán 3er piso Ave., Av. Francisco I. Madero s/n y Gonzalitos Col. Mitras Centro, NL, C.P. 64460, Monterrey, Mexico.
Martha Merino RuizCentro Universitario de Medicina Reproductiva, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León. Monterrey, Edificio Rodrigo Barragán 3er piso Ave., Av. Francisco I. Madero s/n y Gonzalitos Col. Mitras Centro, NL, C.P. 64460, Monterrey, Mexico.
Selene Garcia-LunaCentro Universitario de Medicina Reproductiva, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León. Monterrey, Edificio Rodrigo Barragán 3er piso Ave., Av. Francisco I. Madero s/n y Gonzalitos Col. Mitras Centro, NL, C.P. 64460, Monterrey, Mexico.
Otto H Valdés-MartínezCentro Universitario de Medicina Reproductiva, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León. Monterrey, Edificio Rodrigo Barragán 3er piso Ave., Av. Francisco I. Madero s/n y Gonzalitos Col. Mitras Centro, NL, C.P. 64460, Monterrey, Mexico.
Oscar Vidal-GutierezDepartamento de Ginecología y Obstetricia, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, NL, Monterrey, México.
Hospital Universitario Dr José Eleuterio Gonzalez · MXUniversidad Autónoma de Nuevo León · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ovarian function and therefore the ovarian reserve may be compromised by the pathogenesis of autoimmune diseases of which, Hashimoto's thyroiditis (HT) is the most common in women of reproductive age. Furthermore, a prolonged reduction in thyroid hormone concentration results in a broad spectrum of reproductive alteration. Previous reports in the literature have been controversial regarding the impact of hypothyroidism and alterations in the ovarian reserve. Thus, this prospective and comparative study aimed to evaluate the association of hypothyroidism with low ovarian reserve. MATERIALS AND

methodsA subset of 27 patients with primary autoimmune hypothyroidism were compared to healthy women. The ovarian reserve was assessed through the anti-Mullerian hormone (AMH) and the antral follicle count (AFC).

resultsOverall, the two groups did not display significant differences in length of their menstrual cycles neither in the AMH serum levels nor the AFC.

conclusionsNo significant alteration was found in the ovarian reserve of women with HT.

Indexed as

AMHAntral follicle countFSHHypothyroidism

Identifiers

PMID33752726
PMCPMC7983266
OpenAlexW3138666970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.