ArticleNutrition & metabolism2021
An optimal glycemic load range is better for reducing obesity and diabetes risk among middle-aged and elderly adults.
Article in Nutrition & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Associations of Glycemic Index and Glycemic Load with Cardiovascular Disease: Updated Evidence from Meta-analysis and Cohort Studies.Current cardiology reports · 2022Pooled it
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundDue to the lack of evidence, advice pertaining to glycemic load (GL) can be misleading. Does the excessive restriction of GL, mostly through an extreme reduction in carbohydrate intake, result in a relatively high intake of fat and protein and result in overweight and obesity? This study was performed to initially explore the optimal GL range.
methodsA cross-sectional study involving 2029 participants aged 40 years or older in Guangzhou, China was conducted. Participants were divided into four groups according to cluster analysis. Dietary data were assessed using a previously validated 3-day food record.
resultsInstead of participants with the highest [cluster 1, median (interquartile ranges) GL was 112(107-119)/1000 kcal] and the lowest GL intake [cluster 4, 90(82-96)/1000 kcal], those with moderate GL intakes [clusters 2 and 3, 93(85-102) and 93(85-99)/1000 kcal, respectively] had a lower prevalence of overweight, obesity and diabetes. In addition, clusters 2 and 3 were more consistent with the macronutrient intake reference with adequate micronutrient intake. Therefore, the optimal GL range was determined to be (85-100)/1000 kcal, rather than "lower is better".
conclusionsReducing the GL intake to prevent diabetes deserves more attention in the context of a balanced diet. An appropriate GL may be better than excessive restriction.
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