ArticleBMC women's health2021
Does endometriosis increase susceptibility to COVID-19 infections? A case-control study in women of reproductive age.
Article in BMC women's health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Long COVID and endometriosis: a systematic review and meta-analysis.BMC women's health · 2025Pooled it
- Susceptibility to Infection and Impact of COVID-19 Vaccines on Symptoms of Women with Endometriosis: A Systematic Review and Meta-Analysis of Available Evidence.Reproductive sciences (Thousand Oaks, Calif.) · 2024Pooled it
- Endometriosis and COVID-19: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2022Pooled it
- Structural and Hormonal Changes in Reproductive-Age Women Post-COVID-19: A Cross-Sectional Ultrasound and Biochemical Study.Diagnostics (Basel, Switzerland) · 2025Article
- Evaluation of Long-COVID Syndrome in a Cohort of Patients with Endometriosis or Adenomyosis.Journal of clinical medicine · 2025Article
- Association between the C-reactive protein-triglyceride-glucose index and endometriosis: a cross-sectional study using data from the national health and nutrition examination survey, 1996-2006.BMC women's health · 2025Article
- Is it possible to reduce the rate of vertical transmission and improve perinatal outcomes by inclusion of remdesivir in treatment regimen of pregnant women with COVID-19?BMC pregnancy and childbirth · 2023Article
- Coronavirus diagnosis using cough sounds: Artificial intelligence approaches.Frontiers in artificial intelligence · 2023Article
- The effect of SARS-CoV-2 BNT162b2 vaccine on the symptoms of women with endometriosis.Archives of gynecology and obstetrics · 2023Article
- COVID-19 susceptibility in endometriosis patients: A case control study.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022Article
- Potential impact of COVID-19 pandemic on endometriosis.Reproductive and developmental medicine · 2022Article
- The ongoing impact of the Covid-19 pandemic on endometriosis patients: A survey of 1,089 UK patients.Facts, views & vision in ObGyn · 2022Article
- Mast Cell Activation Syndrome in COVID-19 and Female Reproductive Function: Theoretical Background vs. Accumulating Clinical Evidence.Journal of immunology research · 2022Review
- Are the COVID-19's vaccines efficient on the most dangerous variant of SARS-CoV-2?Clinical and experimental vaccine research · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn today's world, coronavirus disease 2019 (COVID-19) is the most critical health problem and research is continued on studying the associated factors. But it is not clear whether endometriosis increases the risk of COVID-19.
methodsWomen who referred to the gynecology clinic were evaluated and 507 women with endometriosis (case group) were compared with 520 women without endometriosis (control group). COVID-19 infection, symptoms, exposure, hospitalization, isolation, H1N1 infection and vaccination, and past medical history of the participants were recorded and compared between the groups using IBM SPSS Statistics for Windows version 21.
resultsComparison between the groups represent COVID-19 infection in 3.2% of the case group and 3% of the control group (P = 0.942). The control group had a higher frequency of asymptomatic infection (95.7% vs. 94.5%; P < 0.001) and fever (1.6% vs. 0%; P = 0.004), while the frequency of rare symptoms was more common in the case group (P < 0.001). The average disease period was 14 days in both groups (P = 0.694). COVID-19 infection was correlated with close contact (r = 0.331; P < 0.001 in the case group and r = 0.244; P < 0.001 in the control group), but not with the history of thyroid disorders, H1N1 vaccination, traveling to high-risk areas, and social isolation (P > 0.05).
conclusionEndometriosis does not increase the susceptibility to COVID-19 infections, but alters the manifestation of the disease. The prevalence of the disease may depend on the interaction between the virus and the individual's immune system but further studies are required in this regard.
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