ArticleBMC pregnancy and childbirth2021
Maternal-foetal complications in pregnancy: a retrospective comparison between type 1 and type 2 diabetes mellitus.
Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Body Weight-Related Parameters in Pregnancies Complicated by Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis with Maternal and Perinatal Outcome Mapping.Journal of clinical medicine · 2026Review
- Diabetes Monitoring in Pregnant Women with Type 1 Diabetes: Capillary Blood Glucose or Interstitial Fluid Glucose? A Case Control Study.Nutrition and metabolic insights · 2026Article
- Cardiometabolic Risk Factors and Adverse Outcomes in Pregnant Women With Type 2 Diabetes.Journal of the Endocrine Society · 2025Article
- Health Care Providers' Perspectives on Factors Influencing Diabetes Management Among Thai Pregnant Women.Women's health reports (New Rochelle, N.Y.) · 2025Article
- Pregnancy outcomes in type 2 versus type 1 diabetes: systematic review with meta-analyses.Endocrine connections · 2024Article
- Therapeutic Potential of Thunbergia laurifolia L. Extract in Gestational Diabetes Mellitus: Insights from a Rat Model.Chinese journal of integrative medicine · 2024Article
- Exploring maternal and neonatal outcomes in women with Type-1 Diabetes: A study from Pakistan.Pakistan journal of medical sciences · 2024Article
- Prematurity and congenital malformations differ according to the type of pregestational diabetes.BMC pregnancy and childbirth · 2024Observational
- Bone Mass Accrual in First Six Months of Life: Impact of Maternal Diabetes, Infant Adiposity, and Cord Blood Adipokines.Calcified tissue international · 2022Article
- Myoinositol supplementation in the treatment of gestational diabetes mellitus: effects on glycaemic control and maternal-foetal outcomes.BMC pregnancy and childbirth · 2022Article
- Is Glycated Hemoglobin A1c Level Associated with Adverse Pregnancy Outcomes of Women Affected by Pre-Gestational Diabetes?Medicina (Kaunas, Lithuania) · 2021Observational
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the study was a retrospective comparison of the differences in maternal-foetal outcomes between women with type 1 and type 2 diabetes mellitus (T1DM and T2DM).
methodsA cohort of 135 patients with pregestational diabetes, 73 with T1DM (mean age 29 ± 5 years) and 62 with T2DM (mean age 33 ± 6 years), in intensive insulin treatment throughout pregnancy were evaluated. Clinical and metabolic parameters and the prevalence of maternal and foetal complications were assessed.
resultsWomen with T1DM showed lower pregestational BMI (p < 0.001), pregestational weight (p < 0.001), weight at delivery (p < 0.001), ∆_total_insulin requirement (IR) at the first, second and third trimesters (all p < 0.001) and higher weight gain during pregnancy (p < 0.001), pregestational HbA1c (p = 0.040), HbA1c in the first (p = 0.004), second (p = 0.020) and third (p = 0.010) trimesters compared to T2DM. Women with T1DM had a higher risk of macrosomia (p = 0.005) than T2DM, while women with T2DM showed higher prevalence of abortion (p = 0.037) than T1DM. At multivariate analysis, pregestational BMI and ∆_total_IR of the first trimester were independently associated with abortion in T2DM, while weight gain during pregnancy was independently associated with macrosomia in T1DM.
conclusionWomen with T1DM have a higher risk of macrosomia than T2DM due to weight gain throughout pregnancy. By contrast, women with T2DM have a higher risk of spontaneous abortion than T1DM, due to pregestational BMI and ∆_total_IR in the first trimester.
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