Evidence map›Paper›PMID 33752534›Full record

ArticleInternational journal of STD & AIDS2021

Likely clinical depression and HIV-related decline in antiretroviral therapy untreated women who seroconverted during participation in microbicide trials in sub-Saharan Africa.

Christine T Rael, Sarah Roberts, Mbolaji Ibitoye, Pamina M Gorbach, Thesla Palanee-Phillips, Ishana Harkoo, Yamikani Mbilizi, Ravindre Panchia, Samantha Siva, Tchangani Tembo and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of STD & AIDS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 4 countries.

Christine T RaelDivision of Gender, Sexuality, and Health, HIV Center for Clinical and Behavioral Studies at the New York State Psychiatric Institute and Columbia University, New York, NY, USA.ORCID 0000-0002-6303-3809
Sarah RobertsWomen's Global Health Imperative, RTI International, San Francisco, CA, USA.
Mbolaji IbitoyeMailman School of Public Health, Columbia University, New York, NY, USA.ORCID 0000-0003-4820-0805
Pamina M GorbachDepartment of Epidemiology, Fielding School of Public Health, 8783University of California, Los Angeles, Los Angeles, CA, USA.
Thesla Palanee-PhillipsFaculty of Health Sciences, School of Clinical Medicine, Wits Reproductive Health and HIV Institute (Wits RHI), University of the Witwatersrand, Johannesburg, South Africa.
Ishana HarkooCenter for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Yamikani MbiliziBlantyre CRS - Johns Hopkins Research Project, Blantyre, Malawi.
Ravindre PanchiaPerinatal HIV Research Unit (PHRU), Chris Hani Baragwanath Academic Hospital, 196579University of the Witwatersrand, Johannesburg, South Africa.
Samantha SivaHIV Prevention Research Unit, South African Medical Research Council, Durban, South Africa.
Tchangani TemboUNC Project, Kamuzu Central Hospital, Lilongwe, Malawi.
Carolyne Agwau AkelloJohns Hopkins Research Collaboration, Makerare University, Kampala, Uganda.
Jennifer BalkusDepartment of Epidemiology, 7284University of Washington, Seattle, WA, USA.
Sharon RiddlerDepartment of Medicine/Infectious Diseases, 6614University of Pittsburgh, Pittsburgh, PA, USA.
Alex Carballo-DiéguezDivision of Gender, Sexuality, and Health, HIV Center for Clinical and Behavioral Studies at the New York State Psychiatric Institute and Columbia University, New York, NY, USA.
New York Psychoanalytic Society and Institute · USUniversity of the Witwatersrand · ZABlantyre Institute for Community Ophthalmology · MWCentre for the AIDS Programme of Research in South Africa · ZAColumbia University · USKamuzu Central Hospital · MWMUJHU Research Collaboration · UGRTI International · USSouth African Medical Research Council · ZAUniversity of California, Los Angeles · USUniversity of Pittsburgh · USUniversity of Washington · US

Funding

Microbicide Trials NetworkUM1AI068633 · NIAID · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI HILLIER, SHARON L. · 2011 to 2021
$175.0M
Microbicide Trials NetworkU01AI068633 · NIAID · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI HILLIER, SHARON L. · 2006 to 2010
$77.0M
Statistical and Data Management Center (SDMC): Microbicide Trials NetworkUM1AI068615 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BROWN, ELIZABETH RENATA · 2011 to 2021
$66.5M
WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Alan David Levine · 1994 to 2026
$50.0M
The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Claude Ann Mellins · 2003 to 2026
$48.2M
The Malawi Clinical Trials UnitUM1AI069518 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JACKY M JENNINGS, TAHA E TAHA · 2012 to 2026
$43.8M
The Johns Hopkins University - Uganda Clinical Trials UnitUM1AI069530 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MARY Glenn Fowler, Philippa Musoke · 2012 to 2026
$34.8M
Laboratory Center (LC): Microbicide Trials NetworkUM1AI106707 · NIAID · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI MELLORS, JOHN W, ROHAN, LISA CENCIA · 2014 to 2021
$27.1M
Supplement: Developing Tailored Delivery and Adherence Interventions for use of Long-Acting Biomedical HIV Prevention Strategies by Transgender WomenK01MH115785 · NIMH · UNIVERSITY OF COLORADO DENVER · PI RAEL, CHRISTINE TAGLIAFERRI · 2018 to 2022
$767k
NIAID NIH HHS P30 AI036219NIAID NIH HHS U01 AI068633NIAID NIH HHS UM1 AI068615NIAID NIH HHS UM1 AI068633NIAID NIH HHS UM1 AI069518NIAID NIH HHS UM1 AI069530NIAID NIH HHS UM1 AI106707NIMH NIH HHS K01 MH115785NIMH NIH HHS P30 MH043520
6 · The paper itself

Abstract

Depression worsens HIV outcomes in populations treated with antiretroviral therapy (ART) medications. Data are limited on the relationship between depression and HIV in untreated populations in sub-Saharan Africa. We aimed to identify associations between likely clinical depression, alcohol use, social support by partners, and HIV viral load (VL) among ART untreated women who recently became HIV positive and enrolled in the Microbicide Trials Network (MTN)-015 study. Analyses used cross-sectional data collected at baseline in MTN-015. Participants in this analysis (

Indexed as

Anti-HIV AgentsAnti-Infective AgentsHIV InfectionsCross-Sectional StudiesDepressionFemaleHumansMaleViral LoadAnti-HIV AgentsAnti-Infective Agents

Identifiers

PMID33752534
PMCPMC8594455
OpenAlexW3138713541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.