Evidence map›Paper›PMID 33752478›Full record

SynthesisInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2021

Efficacy and safety of flow diverters in posterior circulation aneurysms and comparison with their efficacy in anterior circulation aneurysms: A systematic review and meta-analysis.

Mohamed Abdel-Tawab, Ahmed K Abdeltawab, Mohamed Abdelmonem, Mahmoud A Moubark, Mohamed Ah Taha, Abdalla Morsy, Ahmed Awad Bessar, Mahmoud Ahmed Ebada

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Endovascular treatment outcomes of vertebrobasilar junction aneurysms: Systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mohamed Abdel-TawabDepartment of Diagnostic and Interventional Radiology, Assiut University Hospitals, Assiut, Egypt.
Ahmed K AbdeltawabFaculty of Medicine, Fayoum University, Fayoum, Egypt.
Mohamed AbdelmonemFaculty of Medicine, Fayoum University, Fayoum, Egypt.
Mahmoud A MoubarkDepartment of Diagnostic and Interventional Radiology, Assiut University Hospitals, Assiut, Egypt.
Mohamed Ah TahaDepartment of Vascular and Endovascular Surgery, Assiut University Hospitals, Assiut, Egypt.
Abdalla MorsyDepartment of Neurosurgery, Assiut University Hospitals, Assiut, Egypt.
Ahmed Awad BessarFaculty of Medicine, Zagazig University, Zagazig, Egypt.
Mahmoud Ahmed EbadaFaculty of Medicine, Zagazig University, Zagazig, Egypt.ORCID https://orcid.org/0000-0001-5284-2929
Assiut University Hospitals · EGFayoum University · EGZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to assess the efficacy and safety of flow-diverter stents (FDs) in the management of posterior circulation cerebral aneurysms and compare FD efficacy between anterior and posterior circulation aneurysms.

methodsWe searched the PubMed, Scopus, Cochrane, and Web of Science databases for relevant studies through March 2020. Studies assessing FDs for posterior circulation aneurysms that included ≥20 treated aneurysms were included. Moreover, the studies compared FD efficacy between anterior and posterior circulation aneurysms were included. Data regarding angiographic aneurysmal occlusion, procedural complications, mortality, and morbidity were extracted and pooled in a random-effects meta-analysis model.

resultsFourteen studies with a total of 659 patients and 676 posterior circulation aneurysms were included. The pooled rate of aneurysmal occlusion at long-term angiographic follow-up was 78% [95% confidence interval (CI), 71-85]. The pooled rates of intraparenchymal hemorrhage, ischemia, and procedure-related mortality and neurological morbidity were 2%, 8%, 7%, and 6%, respectively. Complete occlusion occurred in 82.4% of the posterior circulation aneurysm subgroup and 77.5% of the anterior circulation aneurysm subgroup. The difference was not significant (relative risk 1.01; 95% CI, 0.86-1.19; p = 0.91). Regression analysis showed that elderly patients and females had higher morbidity.

conclusionPosterior circulation aneurysms can be effectively treated with FDs with comparable occlusion rates to those in anterior circulation aneurysms. However, periprocedural complications are not negligible.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmAgedAngiographyFemaleHumansRetrospective StudiesStentsTreatment Outcomeendovascular treatmentFlow-diverter devicepipeline embolization deviceposterior circulation aneurysms

Identifiers

PMID33752478
PMCPMC8493351
OpenAlexW3139121487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.