Evidence map›Paper›PMID 33752076›Full record

ArticleNeuroImage. Clinical2021

High-b diffusivity of MS lesions in cervical spinal cord using ultrahigh-b DWI (UHb-DWI).

Kyle Jeong, Lubdha M Shah, You-Jung Lee, Bijaya Thapa, Nabraj Sapkota, Erica Bisson, Noel G Carlson, E K Jeong, John W Rose

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kyle JeongUtah Center for Advanced Imaging Research, University of Utah, Utah, USA.
Lubdha M ShahDepartment of Radiology and Imaging Sciences, University of Utah, Utah, USA.
You-Jung LeeUtah Center for Advanced Imaging Research, University of Utah, Utah, USA.
Bijaya ThapaUtah Center for Advanced Imaging Research, University of Utah, Utah, USA.
Nabraj SapkotaUtah Center for Advanced Imaging Research, University of Utah, Utah, USA.
Erica BissonDepartment of Neurosurgery, University of Utah, Utah, USA.
Noel G CarlsonNeuroimmunology and Neurovirology Division, Department of Neurology, University of Utah, Utah, USA; GRECC, VA Salt Lake City Health Care System, Utah, USA; Department of Neurobiology, University of Utah, Utah, USA.
E K JeongUtah Center for Advanced Imaging Research, University of Utah, Utah, USA; Department of Radiology and Imaging Sciences, University of Utah, Utah, USA.
John W RoseNeuroimmunology and Neurovirology Division, Department of Neurology, University of Utah, Utah, USA; Neurology Service, VA Salt Lake City Health Care System, Utah, USA. Electronic address: jrose@genetics.utah.edu.
University of Utah · USAdvanced Imaging Research (United States) · USGeriatric Research Education and Clinical Center · US

Funding

Quantitative evaluation of myelin damage in cervical spinal cordR56NS106097 · NINDS · UNIVERSITY OF UTAH · PI JEONG, EUN-KEE (E.K.) · 2018 to 2018
$534k
NINDS NIH HHS R56 NS106097
6 · The paper itself

Abstract

purposeThe purpose of this study was to investigate UHb-rDWI signal in white matter tracts of the cervical spinal cord (CSC) and compare quantitative values between healthy control WM with both MS NAWM and MS WM lesions.

methodsUHb-rDWI experiments were performed on (a) 7 MS patients with recently active or chronic lesions in CSC and on (b) 7 healthy control of similar age range and gender distribution to MS subjects. All MRI data were acquired using clinical 3T MRI system. Axial high-b diffusion images were acquired using 2D single-shot DW stimulated EPI with reduced FOV and a CSC-dedicated 8 channel array coil. High-b diffusion coefficient D

resultsThe high-b diffusivity D

conclusionUHb-DWI of the CSC reveals a marked difference in signal-b-curves and D

Indexed as

Cervical CordWhite MatterAnimalsDiffusion Magnetic Resonance ImagingHumansSpinal Cord2D single-shot-DW-stimulated-EPI with reduced-FOV (2D ss-DWSTEPI-rFOV)Cervical spinal cordDiffusion tensor imaging, DTIDiffusion-weighted imaging, DWIMultiple sclerosisUltra-high B diffusion-weighted imaging

Identifiers

PMID33752076
PMCPMC7985401
OpenAlexW3134299094

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.