ReviewPoultry science2021
Ochratoxin A: its impact on poultry gut health and microbiota, an overview.
Review in Poultry science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 83 citations in OpenAlex.
- NPoultry science · 2026Review
- Novel aflatoxin oxidase CotA alleviates aflatoxin BPoultry science · 2026Article
- Targeting Mycotoxin Toxicity: From Molecular Mechanisms to Nutritional Interventions.Veterinary sciences · 2026Review
- Mycotoxins, gut microbiota alterations and liver disease in animals: A scoping review.Cell biology and toxicology · 2026Review
- Probiotic-based mycotoxin detoxification in poultry feed: mechanisms, efficacy, challenges, and future directions for sustainable production.Archives of microbiology · 2026Review
- Microbiome-mycotoxin interactions and probiotic strategies: implications for gut health and cancer.Frontiers in nutrition · 2026Review
- Integrative transcriptome and microbiome analysis reveals ferroptosis-driven duodenal damage caused by Ochratoxin A in mice.Frontiers in immunology · 2026Article
- Gut as a Target of Ochratoxin A: Toxicological Insights and the Role of Microbiota.International journal of molecular sciences · 2025Review
- Mitigation of mycotoxin residues and activation of endogenous stem cells in broiler chickens using a toxin binder: Implications for meat safety and performance enhancement.Veterinary world · 2025Article
- Biosensing Strategies to Monitor Contaminants and Additives on Fish, Meat, Poultry, and Related Products.Biosensors · 2025Review
- Emerging biosensors integrated with microfluidic devices: a promising analytical tool for on-site detection of mycotoxins.NPJ science of food · 2025Review
- Mycotoxins in Broiler Production: Impacts on Growth, Immunity, Vaccine Efficacy, and Food Safety.Toxins · 2025Review
- Simultaneous Detection of Ochratoxin A and Aflatoxin B1 Based on Stable Tuning Fork-shaped DNA Fluorescent Aptasensor.Journal of fluorescence · 2025Article
- Selenomethionine alleviates OTA-induced kidney injury in broilers by modulating ferroptosis.Frontiers in veterinary science · 2025Article
- Detection of Ochratoxin A in Maize and Its Potential Impact on Avian Pathology in Romanian Farms.Life (Basel, Switzerland) · 2024Article
- Review
- Biosensors for Monitoring, Detecting, and Tracking Dissemination of Poultry-Borne Bacterial Pathogens Along the Poultry Value Chain: A Review.Animals : an open access journal from MDPI · 2024Review
- Simultaneous detection of multiple mycotoxins in Radix Dipsaci and estimation of exposure risk for consumers.Scientific reports · 2024Article
- Phytic acid alleviates ochratoxin A-induced renal damage in chicks by modulating ferroptosis and the structure of the intestinal microbiota.Poultry science · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ochratoxin A (OTA) is a widespread mycotoxin, that has strong thermal stability, and is difficult to remove from feed. OTA is nephrotoxic, hepatotoxic, teratogenic, immunotoxic, and enterotoxic to several species of animals. The gut is the first defense barrier against various types of mycotoxins present in feed that enter the body, and it is closely connected to other tissues through enterohepatic circulation. Compared with mammals, poultry is more sensitive to OTA and has a lower absorption rate. Therefore, the gut is an important target tissue for OTA in poultry. This review comprehensively discusses the role of OTA in gut health and the gut microbiota of poultry, focusing on the effect of OTA on digestive and absorptive processes, intestinal barrier integrity, intestinal histomorphology, gut immunity, and gut microbiota. According to the studies described to date, OTA can affect gut dysbiosis, including increasing gut permeability, immunity, and bacterial translocation, and can eventually lead to gut and other organ injury. Although there are many studies investigating the effects of OTA on the gut health of poultry, further studies are needed to better characterize the underlying mechanisms of action and develop preventative or therapeutic interventions for mycotoxicosis in poultry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.