Evidence map›Paper›PMID 33751954›Full record

ArticleDevelopmental cognitive neuroscience2021

Delay discounting and neurocognitive correlates among inner city adolescents with and without family history of substance use disorder.

Diana V Rodriguez-Moreno, Yael M Cycowicz, Bernd Figner, Zhishun Wang, Xiaofu He, Lupo Geronazzo-Alman, Xiaoxiao Sun, Keely Cheslack-Postava, Adam Bisaga, Christina W Hoven and 1 more

Open access · goldAbstract read
In one paragraph

Article in Developmental cognitive neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

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  8. Sex differences in stress responses among underrepresented minority adolescents at risk for substance use disorder.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Diana V Rodriguez-MorenoNew York State Psychiatric Institute, New York, NY, United States. Electronic address: Diana.Moreno@nyspi.columbia.edu.
Yael M CycowiczNew York State Psychiatric Institute, New York, NY, United States; Department of Psychiatry, Columbia University, New York, NY, United States. Electronic address: yc60@cumc.columbia.edu.
Bernd FignerBehavioural Science Institute and Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.
Zhishun WangNew York State Psychiatric Institute, New York, NY, United States; Department of Psychiatry, Columbia University, New York, NY, United States.
Xiaofu HeNew York State Psychiatric Institute, New York, NY, United States; Department of Psychiatry, Columbia University, New York, NY, United States.
Lupo Geronazzo-AlmanNew York State Psychiatric Institute, New York, NY, United States; Department of Psychiatry, Columbia University, New York, NY, United States.
Xiaoxiao SunDepartment of Psychiatry, Columbia University, New York, NY, United States; Department of Bioengineering, Columbia University, New York, NY, United States.
Keely Cheslack-PostavaNew York State Psychiatric Institute, New York, NY, United States; Department of Psychiatry, Columbia University, New York, NY, United States.
Adam BisagaNew York State Psychiatric Institute, New York, NY, United States; Department of Psychiatry, Columbia University, New York, NY, United States.
Christina W HovenNew York State Psychiatric Institute, New York, NY, United States; Department of Psychiatry, Columbia University, New York, NY, United States; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States.
Lawrence V AmselNew York State Psychiatric Institute, New York, NY, United States; Department of Psychiatry, Columbia University, New York, NY, United States.
New York Psychoanalytic Society and Institute · USColumbia University · USColumbia University Irving Medical Center · USRadboud University Nijmegen · NL

Funding

Cognitive Control in Children of SUD Parents: A Longitudinal Multimodal MRI StudyR01DA038154 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HOVEN, CHRISTINA W. · 2015 to 2020
$4.4M
NIDA NIH HHS R01 DA038154
6 · The paper itself

Abstract

Adolescents with a family history (FH+) of substance use disorder (SUD) are at a greater risk for SUD, suggested to be partly due to the transmission of behavioral impulsivity. We used a delay discounting task to compare impulsivity in decision-making and its associated brain functioning among FH+ and FH - minority adolescents. Participants chose between Smaller Sooner (SS) and Larger Later (LL) rewards. The SS was available immediately (Now trials) or in the future (Not-Now trials), allowing for greater differentiation between impulsive decisions. The FH+ group showed greater impatience by responding SS more frequently than the FH - group, only on the Now trials, and even when the relative reward differences (RRD) increased. Surprisingly, there were no differences in brain activity between the groups. Combined, the groups showed greater reward activity during the Now vs. Not-Now trials in medial prefrontal/anterior cingulate, posterior cingulate, precuneus, and inferior frontal gyrus (i.e., an immediacy effect). As the RRD increased activation in the reward network decreased, including the striatum, possibly reflecting easy decision-making. These results indicate that risk for SUD, seen behaviorally among FH+ adolescents, may not yet be associated with discernable brain changes, suggesting that early intervention has the potential to reduce this risk.

Indexed as

Delay DiscountingSubstance-Related DisordersAdolescentChildDiffusion Tensor ImagingFemaleHumansImpulsive BehaviorMagnetic Resonance ImagingMaleRewardDelay discountingFamily historyfMRISubstance use disorder

Identifiers

PMID33751954
PMCPMC8010627
OpenAlexW3133989046

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.