Evidence map›Paper›PMID 33751756›Full record

ArticleDermatologic therapy2021

Chitin-lipid interactions and the potential relationship between Demodex and SARS-CoV-2.

Alin Laurentiu Tatu, Thomas Nadasdy, Lawrence Chukwudi Nwabudike

Open access · greenAbstract read
In one paragraph

Article in Dermatologic therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alin Laurentiu TatuDermatology Department, "St. Parascheva" Clinical Hospital of Infectious Diseases, Galati, Romania.ORCID 0000-0003-4290-7068
Thomas NadasdyDermatology Department, "St. Parascheva" Clinical Hospital of Infectious Diseases, Galati, Romania.ORCID 0000-0002-1196-8100
Lawrence Chukwudi NwabudikeN. Paulescu National Institute of Diabetes, Bucharest, Romania.ORCID 0000-0003-0774-7396
Clinical Emergency Hospital Bucharest · ROTitu Maiorescu University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Already from the early days of the COVID-19 pandemic, regulatory agencies have attempted to ascertain the possible routes of SARS-CoV-2 viral transmission. It is hypothesized that the lipid bilayer that surrounds the SARS-CoV-2 improves its ability to remain stable on sebum-rich skin and serves as another possible route of contracting the virus. One possible aspect of these observations that has yet to be explored in detail is what role arthropods that have been associated with human skin infestation, such as Demodecidae or Pyemotidae species, play in viral transmission. It seems likely that arthropod-coronavirus interactions may take place through the molecular attraction forces between the chitin found on the exoskeleton of mites commonly found on human skin and the lipids present on the viral envelope of the SARS-CoV-2. We believe this may mean that arthropods are currently an overlooked cofactor in viral infection which may have some important biomedical implications for both prevention and treatment.

Indexed as

COVID-19SARS-CoV-2ChitinHumansLipidsPandemicsChitinLipidschitinDemodexSARS-CoV-2

Identifiers

PMID33751756
PMCPMC8206677
OpenAlexW3135598274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.