Evidence map›Paper›PMID 33751687›Full record

ArticleNMR in biomedicine2021

MR spectroscopic imaging at 3 T and outcomes in surgical epilepsy.

Jullie W Pan, Arun Antony, Assaf Tal, Victor Yushmanov, Joanna Fong, Mark Richardson, Claud Schirda, Anto Bagic, Oded Gonen, Hoby P Hetherington

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jullie W PanDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-7805-5568
Arun AntonyDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Assaf TalDepartment of Chemical and Biological Physics, Weizmann Institute, Rehovot, Israel.ORCID 0000-0001-6718-6522
Victor YushmanovDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Joanna FongDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Mark RichardsonDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
Claud SchirdaDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Anto BagicDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Oded GonenDepartment of Radiology, New York University, New York, New York.
Hoby P HetheringtonDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.

Funding

Spectroscopic imaging of human epilepsyR01NS090417 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PAN, JULLIE W · 2014 to 2017
$2.4M
Quantitative Sodium MR Imaging and Proton MR Spectroscopy in Traumatic Brain InjuryR01NS097494 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KIROV, IVAN IVANOV, MADELIN, GUILLAUME · 2016 to 2020
$2.4M
7T MR spectroscopic imaging for human epilepsyR01EB011639 · NIBIB · YALE UNIVERSITY · PI HETHERINGTON, HOBY P, PAN, JULLIE W · 2011 to 2014
$2.0M
Multiplexed Multiband MR at 7T: Studies of mild Traumatic Brain InjuryR01NS081772 · NINDS · YALE UNIVERSITY · PI HETHERINGTON, HOBY P · 2012 to 2015
$2.0M
Fast Targeted Spectroscopic Imaging for Brain Tumor Imaging at 3T and 7TR01EB024408 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PAN, JULLIE W · 2018 to 2021
$1.9M
Multiparametric Magnetic Resonance Spectroscopy for the Early Detection of Neurodegeneration in Relapsing-Remitting Multiple SclerosisR21NS112853 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KIROV, IVAN IVANOV, TAL, ASSAF · 2019 to 2019
$417k
NIBIB NIH HHS R01 EB011639NIBIB NIH HHS R01 EB024408NINDS NIH HHS R01 NS081772NINDS NIH HHS R01 NS090417NINDS NIH HHS R01 NS097494NINDS NIH HHS R21 NS112853
6 · The paper itself

Abstract

For the spectroscopic assessment of brain disorders that require large-volume coverage, the requirements of RF performance and field homogeneity are high. For epilepsy, this is also challenging given the inter-patient variation in location, severity and subtlety of anatomical identification and its tendency to involve the temporal region. We apply a targeted method to examine the utility of large-volume MR spectroscopic imaging (MRSI) in surgical epilepsy patients, implementing a two-step acquisition, comprised of a 3D acquisition to cover the fronto-parietal regions, and a contiguous parallel two-slice Hadamard-encoded acquisition to cover the temporal-occipital region, both with T

Indexed as

Magnetic Resonance SpectroscopyAdultAspartic AcidCase-Control StudiesEpilepsyFemaleGray MatterHumansMaleMiddle AgedYoung AdultAspartic AcidN-acetylaspartateepilepsyHadamardrosettespectroscopic imaging

Identifiers

PMID33751687
PMCPMC8122073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.