ArticleHuman brain mapping2021
Early-stage Parkinson's disease: Abnormal nigrosome 1 and 2 revealed by a voxelwise analysis of neuromelanin-sensitive MRI.
Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 20 citations in OpenAlex.
- Neuroimaging of the monoaminergic system in Parkinson's disease: A narrative review.Neuroimage. Reports · 2026Review
- Neuromelanin imaging outperforms free water imaging in diagnosing early Parkinson's disease: a comparative MRI study.NPJ Parkinson's disease · 2026Article
- High-resolution mapping of substantia nigra in Parkinson's disease using 7 tesla magnetic resonance imaging.NPJ Parkinson's disease · 2025Article
- Deep Learning-Based Algorithm for Automatic Quantification of Nigrosome-1 and Parkinsonism Classification Using Susceptibility Map-Weighted MRI.AJNR. American journal of neuroradiology · 2025Article
- Neuromelanin-MRI identifies locus coeruleus and substantia nigra degeneration as key differentiators in isolated rapid eye movement sleep behavior disorder.Brain imaging and behavior · 2025Article
- Neuromelanin-sensitive MRI for mechanistic research and biomarker development in psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Whole brain pattern of iron accumulation in REM sleep behavior disorder.Human brain mapping · 2024Article
- Neuromelanin-sensitive MRI as a promising biomarker of catecholamine function.Brain : a journal of neurology · 2024Review
- Classification of Parkinson's disease by deep learning on midbrain MRI.Frontiers in aging neuroscience · 2024Article
- Ultra-high-field 7T MRI in Parkinson's disease: ready for clinical use?-a narrative review.Quantitative imaging in medicine and surgery · 2023Review
- Diagnostic performance of a high-spatial-resolution voxelwise analysis of neuromelanin-sensitive imaging in early-stage idiopathic Parkinson's disease.BMC medical imaging · 2023Article
- Correlation Between Neuromelanin-Sensitive MRI andJournal of clinical neurology (Seoul, Korea) · 2023Article
- Application of Neuromelanin MR Imaging in Parkinson Disease.Journal of magnetic resonance imaging : JMRI · 2023Review
- The Key Role of Magnetic Resonance Imaging in the Detection of Neurodegenerative Diseases-Associated Biomarkers: A Review.Molecular neurobiology · 2022Review
- Erratum for Early-stage Parkinson's disease: Abnormal nigrosome 1 and 2 revealed by a voxel wise analysis of neuromelanin-sensitive MRI.Human brain mapping · 2022Article
- Modified Iron Deposition in Nigrosomes by Pharmacotherapy for the Management of Parkinson's Disease.Frontiers in molecular biosciences · 2022Article
- Early-stage Parkinson's disease: Abnormal nigrosome 1 and 2 revealed by a voxelwise analysis of neuromelanin-sensitive MRI.Human brain mapping · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous pathologic studies evaluated the substantia nigra pars compacta (SNpc) of a limited number of idiopathic Parkinson's disease (IPD) patients with relatively longer disease durations. Therefore, it remains unknown which region of the SNpc is most significantly affected in early-stage IPD. We hypothesized that a voxelwise analysis of thin-section neuromelanin-sensitive MRI (NM-MRI) may help determine the significantly affected regions of the SNpc in early-stage IPD and localize these areas in each nigrosome on high-spatial-resolution susceptibility map-weighted imaging (SMwI). Ninety-six healthy subjects and 50 early-stage IPD patients underwent both a 0.8 × 0.8 × 0.8 mm
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.