SynthesisJournal of orthopaedic research : official publication of the Orthopaedic Research Society2021
Meniscal repair: The current state and recent advances in augmentation.
Synthesis in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of proprioceptive training in the recovery of patients submitted to meniscus surgery: systematic review and meta-analysis.BMJ open · 2022Pooled it
- First-in-human exploratory trial assessing safety, feasibility, and efficacy of artificial protein (silk-elastin) in promoting healing in patients with meniscus injuries.Scientific reports · 2025Trial
- The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy: a randomized, double-blind, placebo-controlled study.BMC musculoskeletal disorders · 2025Trial
- Meniscal Repair Achieves Comparable Mid-Term Functional Performance to Partial Meniscectomy Following Anterior Cruciate Ligament Reconstruction in Highly Active Patients.Orthopaedic surgery · 2026Article
- Hybrid Sequential Meniscal Suture Technique.Arthroscopy techniques · 2026Article
- Patients 40 Years of Age or Older Have Comparable Return to Sport Rates, Reinjury Rates, and 2-Year Patient-Reported Outcomes After Medial or Lateral Meniscus Repair Compared With Patients Younger Than 40 Years of Age.Arthroscopy, sports medicine, and rehabilitation · 2026Article
- Identification and characterization of POSTNJournal of orthopaedic translation · 2026Article
- [Advances in immunomodulatory strategies for meniscal regeneration].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Optimizing Anatomic Reduction of Vertical Meniscus Tears With All-Inside Meniscus Repair.Arthroscopy techniques · 2026Article
- Diagnostic value of postoperative magnetic resonance imaging in predicting clinical outcomes after meniscal repair: A retrospective cohort study.International orthopaedics · 2026Observational
- Meniscectomy vs Meniscal Repair: Comparing Rates of Readmission, Reoperation, and Osteoarthritis.Orthopaedic journal of sports medicine · 2026Article
- Rethinking meniscal repair in patients over 40: Extending the boundaries of joint preservation.World journal of methodology · 2026Review
- Pneumatospinning and Electrospinning Scaffolds for Meniscus Regeneration Using Human Embryonic-Derived Mesenchymal Stem Cells.Bioengineering (Basel, Switzerland) · 2026Article
- Evaluating the efficacy and safety of an all-inside, all-suture meniscal repair device on arthroscopic meniscal repair: a prospective, multi-center, randomized controlled clinical trial.International journal of surgery (London, England) · 2026Article
- Surgical Volume of ACL Reconstruction, Knee Arthroscopy, and Rotator Cuff Repair Before and After the COVID-19 Pandemic: National Surgical Quality Improvement Program Data from 2015 to 2022.Orthopaedic journal of sports medicine · 2026Article
- Biologic Augmentation for Meniscus Repair: A Narrative Review.Bioengineering (Basel, Switzerland) · 2026Review
- Integrated strategies in meniscus tissue engineering: from biomaterials to stem cell-driven regeneration.Frontiers in bioengineering and biotechnology · 2026Review
- Nonionic Surfactant as a Tool to Modify Electrospun Fiber Properties for In Vitro Fibrous Connective Tissue Models.Journal of biomedical materials research. Part A · 2026Article
- Multi-functional Small Molecule for Regenerative Healing of Avascular Meniscus Tears: Modulation of Inflammation, Differentiation, and Multi-Tissue Crosstalk.Theranostics · 2026Article
- Iliotibial Band Meniscal Augmentation for a Revision Inside-Out Lateral Meniscus Radial and Horizontal Cleavage Tear Repair.Arthroscopy techniques · 2026Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Meniscal injuries represent one of the most common orthopedic injuries. The most frequent treatment is partial resection of the meniscus, or meniscectomy, which can affect joint mechanics and health. For this reason, the field has shifted gradually towards suture repair, with the intent of preservation of the tissue. "Save the Meniscus" is now a prolific theme in the field; however, meniscal repair can be challenging and ineffective in many scenarios. The objectives of this review are to present the current state of surgical management of meniscal injuries and to explore current approaches being developed to enhance meniscal repair. Through a systematic literature review, we identified meniscal tear classifications and prevalence, approaches being used to improve meniscal repair, and biological- and material-based systems being developed to promote meniscal healing. We found that biologic augmentation typically aims to improve cellular incorporation to the wound site, vascularization in the inner zones, matrix deposition, and inflammatory relief. Furthermore, materials can be used, both with and without contained biologics, to further support matrix deposition and tear integration, and novel tissue adhesives may provide the mechanical integrity that the meniscus requires. Altogether, evaluation of these approaches in relevant in vitro and in vivo models provides new insights into the mechanisms needed to salvage meniscal tissue, and along with regulatory considerations, may justify translation to the clinic. With the need to restore long-term function to injured menisci, biologists, engineers, and clinicians are developing novel approaches to enhance the future of robust and consistent meniscal reparative techniques.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.