Evidence map›Paper›PMID 33751313›Full record

ArticleAIDS and behavior2021

Use of Pre-exposure Prophylaxis Among People Who Inject Drugs: Exploratory Findings of the Interaction Between Race, Homelessness, and Trust.

Xin Zhou, Frederick L Altice, Divya Chandra, Elizabeth Didomizio, Michael M Copenhaver, Roman Shrestha

Abstract read
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In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xin ZhouSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 135 College Street, Suite 355, New Haven, CT, 06510, USA. xin.zhou19@yale.edu.ORCID http://orcid.org/0000-0003-2852-1468
Frederick L AlticeSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 135 College Street, Suite 355, New Haven, CT, 06510, USA.
Divya ChandraSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 135 College Street, Suite 355, New Haven, CT, 06510, USA.
Elizabeth DidomizioSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 135 College Street, Suite 355, New Haven, CT, 06510, USA.
Michael M CopenhaverInstitute for Collaboration on Health, Intervention, and Policy (InCHIP), University of Connecticut, Storrs, CT, USA.
Roman ShresthaSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 135 College Street, Suite 355, New Haven, CT, 06510, USA.
University of Connecticut · USYale University · US

Funding

Secondary HIV Prevention and Adherence Among HIV-infected Drug UsersR01DA032290 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI COPENHAVER, MICHAEL · 2012 to 2016
$3.1M
Enhancing Health Outcomes Among HIV+ Substance AbusersK24DA017072 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2003 to 2012
$1.5M
Optimizing HIV Prevention Among Opioid-Dependent PersonsK24DA051344 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI MICHAEL COPENHAVER · 2020 to 2026
$1.3M
Training in MHealth Prevention with MSMK01DA051346 · NIDA · YALE UNIVERSITY · PI SHRESTHA, ROMAN · 2020 to 2024
$862k
NIDA NIH HHS K01DA051346NIDA NIH HHS K24DA017072NIDA NIH HHS K24DA051344NIDA NIH HHS R01DA032290
6 · The paper itself

Abstract

Scale-up of pre-exposure prophylaxis (PrEP) in people who inject drugs (PWID) remains suboptimal. Patient-level factors are often complex and may contribute to scale-up. Using cross-sectional data from 234 opioid-dependent patients on methadone who met eligibility criteria for PrEP, we conducted logistic regression analyses to assess potential moderators associated with being on PrEP (n = 60). Mean provider trust was significantly higher among Blacks vs Whites (39.4 vs 34.9; p = 0.002) and non-homeless vs homeless participants (37.5 vs 34.8; p = 0.008). Though race/ethnicity was not a significant moderator on provider trust and PrEP use, increased provider trust was marginally associated with increased PrEP use among Blacks (p = 0.058). Additionally, homelessness significantly moderated provider trust and PrEP use (p = 0.024). Provider trust among non-homeless participants was positively correlated with PrEP use (p = 0.013) but not among homeless participants. Strategies that promote provider trust in Blacks and non-homeless PWID on methadone may improve PrEP scale-up.

Indexed as

Anti-HIV AgentsHIV InfectionsIll-Housed PersonsPharmaceutical PreparationsPre-Exposure ProphylaxisSubstance Abuse, IntravenousCross-Sectional StudiesHumansTrustAnti-HIV AgentsPharmaceutical PreparationsEthnic disparitiesMethadone maintenance treatmentPeople who inject drugs (PWID)Pre-exposure prophylaxis (PrEP)Provider trust

Identifiers

PMID33751313
OpenAlexW3139322209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.