ArticleCancer causes & control : CCC2021
Incidence rates and contemporary trends in primary urethral cancer.
Article in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Multimodal Treatment for Female Primary Urethral Carcinoma: A Three-Case Series Utilizing Robot-Assisted Radical Cystectomy and Extended Resection.IJU case reports · 2026Article
- Rare urologic malignancies in solid organ transplant recipients.Current urology · 2026Article
- Real-World Treatment Patterns and Outcomes of Intraluminal Ablative Therapies in Noninvasive Urethral Carcinoma: A National Cancer Database Analysis.Current oncology (Toronto, Ont.) · 2026Article
- Müllerian-type clear cell adenocarcinoma of the urethra: a case report.Einstein (Sao Paulo, Brazil) · 2026Article
- Radiotherapy for Primary Urethral Carcinoma (PUC): An Illustrative and Narrative Review.Clinical and translational radiation oncology · 2026Review
- Urethrectomy with glans reconstruction and meatoplasty for rare high-grade urothelial carcinoma in distal urethra.Urology case reports · 2026Article
- Female Urethral Adenocarcinoma Posing a Diagnostic Challenge.Clinical case reports · 2025Article
- Effect of chemotherapy on cancer specific mortality in female locally advanced urethral cancer.World journal of urology · 2025Article
- New Trends and Future Perspectives in the Diagnosis of Urothelial Carcinoma: A Comprehensive Review of the Literature.Medicina (Kaunas, Lithuania) · 2025Review
- Primary large cell neuroendocrine carcinoma of the urethra: a case report.Frontiers in urology · 2025Article
- A diagnostic approach of various urethral diseases using multimodal imaging findings: comprehensive overview.Abdominal radiology (New York) · 2024Review
- Primary urethral carcinoma in female: An extremely rare case series at a single tertiary referral hospital and literature review.International journal of surgery case reports · 2024Article
- Association between body mass index, metabolic syndrome and common urologic conditions: a cross-sectional study using a large multi-institutional database from the United States.Annals of medicine · 2023Article
- Morphologic spectrum of the epithelial tumors of the male and female urethra.Virchows Archiv : an international journal of pathology · 2023Review
- A case report: Female primary urethral carcinoma presenting as vulval mass.International journal of surgery case reports · 2023Article
- Epidemiology of Unconventional Histological Subtypes of Urethral Cancer.Urologia internationalis · 2023Article
- Primary urethral carcinoma with variant histology: A case report and literature review.Molecular and clinical oncology · 2022Article
- A brief review on the diagnostic and therapeutic principles of primary urethral cancer.Asian journal of urology · 2022Review
- Temporal trends, tumor characteristics and stage-specific survival in penile non-squamous cell carcinoma vs. squamous cell carcinoma.Cancer causes & control : CCC · 2022Article
- A Primary Urothelial Carcinoma Presenting as a Mid-Bulbar Urethral Stricture in a 30-Year-Old Male.Cureus · 2021Article
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Authors and funding
14 authors.
Funding
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Abstract
purposeWe assessed contemporary incidence rates and trends of primary urethral cancer.
methodsWe identified urethral cancer patients within Surveillance, Epidemiology and End Results registry (SEER, 2004-2016). Age-standardized incidence rates per 1,000,000 (ASR) were calculated. Log linear regression analyses were used to compute average annual percent change (AAPC).
resultsFrom 2004 to 2016, 1907 patients with urethral cancer were diagnosed (ASR 1.69; AAPC: -0.98%, p = 0.3). ASR rates were higher in males than in females (2.70 vs. 0.55), respectively and did not change over the time (both p = 0.3). Highest incidence rates were recorded in respectively ≥75 (0.77), 55-74 (0.71) and ≤54 (0.19) years of age categories, in that order. African Americans exhibited highest incidence rate (3.33) followed by Caucasians (1.72), other race groups (1.57) and Hispanics (1.57), in that order. A significant decrease occurred over time in Hispanics, but not in other race groups. In African Americans, male and female sex-stratified incidence rates were higher than in any other race group. Urothelial histological subtype exhibited highest incidence rate (0.92), followed by squamous cell carcinoma (0.41), adenocarcinoma (0.29) and other histologies (0.20). In stage stratified analyses, T
conclusionUrethral cancer is rare. Its incidence rates are highest in males, elderly patients, African Americans and in urothelial histological subtype. Most urethral cancer cases are T
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