ReviewInternational microbiology : the official journal of the Spanish Society for Microbiology2021
Oral lichen planus: a microbiologist point of view.
Review in International microbiology : the official journal of the Spanish Society for Microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Use of platelet-rich plasma (PRP) and injectable platelet-rich fibrin (i-PRF) in oral lichen planus treatment: a systematic review of randomized controlled trials.BMC oral health · 2025Pooled it
- Efficacy and safety of gut microbiota-based therapies in autoimmune and rheumatic diseases: a systematic review and meta-analysis of 80 randomized controlled trials.BMC medicine · 2024Pooled it
- Disrupted Salivary Fungal Community in Patients With Oral Lichen Planus.International dental journal · 2026Article
- IFN-I Induces Keratinocytes Necroptosis via ZBP1-MLKL Axis in Oral Lichen Planus.Inflammation · 2026Article
- Emerging Role of the NLRP3 Inflammasome in the Onset of Oral Diseases and Its Potential as a Therapeutic Target.International journal of molecular sciences · 2026Review
- Article
- Characteristics of salivary IgA responses to oral microbiota in patients with oral lichen planus.Scientific reports · 2025Article
- Long-Term Efficacy of 5-ALA Photodynamic Therapy in Oral Lichen Planus Patients.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Lichen Planus Following COVID-19 Infection and Vaccination. Matched Case-Control Study.The Australasian journal of dermatology · 2025Article
- DnaK of Parvimonas micra extracellular vesicles interacts with the host fibroblasts BAG3-IKK-γ axis to accelerate TNF-α secretion in oral lichen planus.Microbiome · 2025Article
- Etiopathogenesis of Oral Lichen Planus: A Review.Head and neck pathology · 2025Review
- Microbiome analysis in individuals with human papillomavirus oral infection.Scientific reports · 2025Article
- The oncogenic potential of salivary microRNA-93 and microRNA-412-3p in oral lichen planus: a case-control study.BDJ open · 2024Article
- Tinidazole mouth rinse for the treatment of oral lichen planus: an observational pilot study.BMC oral health · 2024Observational
- Impact of exosomes in oral lichen planus: A review with insights into pathogenesis and biomarkers.Journal of dental sciences · 2024Review
- Association between oral lichen planus and Candida albicans infection: a systematic review and meta-analysis.American journal of translational research · 2024Review
- Psychological Functioning of Women Diagnosed with Lichen Planus and Other Diseases of the Oral Cavity-Explorative Study.Healthcare (Basel, Switzerland) · 2023Article
- Single-cell immune profiling reveals immune responses in oral lichen planus.Frontiers in immunology · 2023Article
- Oral Papillomatosis: Its Relation with Human Papilloma Virus Infection and Local Immunity-An Update.Medicina (Kaunas, Lithuania) · 2022Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral lichen planus (OLP) is a chronic disease of uncertain etiology, although it is generally considered as an immune-mediated disease that affects the mucous membranes and even the skin and nails. Over the years, this disease was attributed to a variety of causes, including different types of microorganisms. This review analyzes the present state of the art of the disease, from a microbiological point of view, while considering whether or not the possibility of a microbial origin for the disease can be supported. From the evidence presented here, OLP should be considered an immunological disease, as it was initially proposed, as opposed to an illness of microbiological origin. The different microorganisms so far described as putative disease-causing agents do not fulfill Koch's postulates; they are, actually, not the cause, but a result of the disease that provides the right circumstances for microbial colonization. This means that, at this stage, and unless new data becomes available, no microorganism can be envisaged as the causative agent of lichen planus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.