Evidence map›Paper›PMID 33751232›Full record

ArticleHandbook of experimental pharmacology2021

Brain Plasma Membrane Monoamine Transporter in Health and Disease.

Letícia S Vieira, Joanne Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Handbook of experimental pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
10.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Dopamine internalization via UptakeFrontiers in pharmacology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Drug metabolism and disposition: the biological fate of chemicals · 2022
    Article
  12. Article
  13. Organic Cation Transporters in Psychiatric Disorders.Handbook of experimental pharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Letícia S VieiraDepartment of Pharmaceutics, Health Sciences Center, University of Washington, Seattle, WA, USA.
Joanne WangDepartment of Pharmaceutics, Health Sciences Center, University of Washington, Seattle, WA, USA. jowang@uw.edu.
University of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise control of monoamine neurotransmitter levels in the central nervous system (CNS) is crucial for proper brain function. Dysfunctional monoamine signaling is associated with several neuropsychiatric and neurodegenerative disorders. The plasma membrane monoamine transporter (PMAT) is a new polyspecific organic cation transporter encoded by the SLC29A4 gene. Capable of transporting monoamine neurotransmitters with low affinity and high capacity, PMAT represents a major uptake

Indexed as

BrainDopamineAnimalsBiological TransportCell MembraneSerotoninSerotonin Plasma Membrane Transport ProteinsDopamineSerotoninSerotonin Plasma Membrane Transport Proteins5-HTAutismBrainCatecholamineChoroid plexusDepressionMonoamine neurotransmitterMPP+OCT3Organic cationPMATSlc29a4 knockoutUptake1Uptake2

Identifiers

PMID33751232
OpenAlexW3135873434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.