Evidence map›Paper›PMID 33750990›Full record

ArticlePloS one2021

Non-COVID-19 patients in times of pandemic: Emergency department visits, hospitalizations and cause-specific mortality in Northern Italy.

Luca Santi, Davide Golinelli, Andrea Tampieri, Gabriele Farina, Manfredi Greco, Simona Rosa, Michelle Beleffi, Bianca Biavati, Francesca Campinoti, Stefania Guerrini and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 3 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 3 syntheses or guidelines pooled it, 189 citations in OpenAlex.

  1. Impact of COVID-19 Pandemic on Adherence to Chronic Therapies: A Systematic Review.International journal of environmental research and public health · 2023
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  15. Efficiency of hospitals in COVID-19 era: a case study of an affected country.Cost effectiveness and resource allocation : C/E · 2024
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Luca SantiDepartment of Emergency, Medicina d'Urgenza e Pronto Soccorso, Policlinico S. Orsola-Malpighi, Bologna, Italy.ORCID 0000-0002-6255-4442
Davide GolinelliDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Andrea TampieriDepartment of Emergency, Medicina d'Urgenza e Pronto Soccorso. Ospedale S. Maria della Scaletta, Imola, Italy.
Gabriele FarinaDepartment of Emergency, Medicina d'Urgenza e Pronto Soccorso, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Manfredi GrecoDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum - University of Bologna, Bologna, Italy.ORCID 0000-0001-6866-1428
Simona RosaDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Michelle BeleffiEmergency Medicine Specialization School, Alma Mater Studiorum - Università di Bologna, Bologna, Italy.
Bianca BiavatiEmergency Medicine Specialization School, Alma Mater Studiorum - Università di Bologna, Bologna, Italy.
Francesca CampinotiEmergency Medicine Specialization School, Alma Mater Studiorum - Università di Bologna, Bologna, Italy.
Stefania GuerriniDepartment of Emergency, Medicina d'Urgenza e Pronto Soccorso, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Rodolfo FerrariDepartment of Emergency, Medicina d'Urgenza e Pronto Soccorso. Ospedale S. Maria della Scaletta, Imola, Italy.
Paola RucciDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Maria Pia FantiniDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Fabrizio GiostraDepartment of Emergency, Medicina d'Urgenza e Pronto Soccorso, Policlinico S. Orsola-Malpighi, Bologna, Italy.
University of Bologna · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITOspedale Santa Maria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic forced healthcare services organization to adjust to mutating healthcare needs. Not exhaustive data are available on the consequences of this on non-COVID-19 patients. The aim of this study was to assess the impact of the pandemic on non-COVID-19 patients living in a one-million inhabitants' area in Northern Italy (Bologna Metropolitan Area-BMA), analyzing time trends of Emergency Department (ED) visits, hospitalizations and mortality. We conducted a retrospective observational study using data extracted from BMA healthcare informative systems. Weekly trends of ED visits, hospitalizations, in- and out-of-hospital, all-cause and cause-specific mortality between December 1st, 2019 to May 31st, 2020, were compared with those of the same period of the previous year. Non-COVID-19 ED visits and hospitalizations showed a stable trend until the first Italian case of COVID-19 has been recorded, on February 19th, 2020, when they dropped simultaneously. The reduction of ED visits was observed in all age groups and across all severity and diagnosis groups. In the lockdown period a significant increase was found in overall out-of-hospital mortality (43.2%) and cause-specific out-of-hospital mortality related to neoplasms (76.7%), endocrine, nutritional and metabolic (79.5%) as well as cardiovascular (32.7%) diseases. The pandemic caused a sudden drop of ED visits and hospitalizations of non-COVID-19 patients during the lockdown period, and a concurrent increase in out-of-hospital mortality mainly driven by deaths for neoplasms, cardiovascular and endocrine diseases. As recurrencies of the COVID-19 pandemic are underway, the scenario described in this study might be useful to understand both the population reaction and the healthcare system response at the early phases of the pandemic in terms of reduced demand of care and systems capability in intercepting it.

Indexed as

Cause of DeathCardiovascular DiseasesCOVID-19Emergency Service, HospitalHospitalizationHumansItalyMetabolic DiseasesNeoplasmsPandemicsQuarantineRetrospective StudiesSARS-CoV-2

Identifiers

PMID33750990
PMCPMC7984614
OpenAlexW3138965320

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.