Evidence map›Paper›PMID 33750922›Full record

ReviewNature reviews. Cancer2021

Antigen presentation in cancer: insights into tumour immunogenicity and immune evasion.

Suchit Jhunjhunwala, Christian Hammer, Lélia Delamarre

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 884 papers.

0numbers the graph read from it
0cells of the map it votes in
884citing papers in PubMed
80.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

884 citing papers in PubMed, 1,380 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Spatial AuAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. USP38 promotes breast cancer immune evasion and malignant progression by deubiquitinating and stabilizing PD-L1.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review

824 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Suchit JhunjhunwalaGenentech Inc., South San Francisco, CA, USA. jhunjhunwala.suchit@gene.com.ORCID http://orcid.org/0000-0003-3484-0588
Christian HammerGenentech Inc., South San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-4548-7548
Lélia DelamarreGenentech Inc., South San Francisco, CA, USA. delamarre.lelia@gene.com.ORCID http://orcid.org/0000-0001-9122-5181
Genesys (United States) · USGene Therapy Laboratory · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint blockade, which blocks inhibitory signals of T cell activation, has shown tremendous success in treating cancer, although success still remains limited to a fraction of patients. To date, clinically effective CD8

Indexed as

AnimalsAntigen PresentationAntigens, NeoplasmCD8-Positive T-LymphocytesHumansImmune EvasionImmunomodulationLymphocytes, Tumor-InfiltratingNeoplasmsAntigens, Neoplasm

Identifiers

PMID33750922
OpenAlexW3134443156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.