Evidence map›Paper›PMID 33750919›Full record

ArticleScientific reports2021

Detection of breeding signatures in wheat using a linkage disequilibrium-corrected mapping approach.

Said Dadshani, Boby Mathew, Agim Ballvora, Annaliese S Mason, Jens Léon

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Harnessing artificial intelligence in plant breeding: innovations in digital phenotyping and breeding methodologies.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  10. Novel PHOTOPERIOD-1 gene variants associate with yield-related and root-angle traits in European bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
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  19. Identification of QTLs for wheat heading time across multiple-environments.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Said DadshaniInstitute of Crop Science and Resource Conservation (INRES), Plant Breeding, University of Bonn, Bonn, Germany. dadshani@uni-bonn.de.
Boby MathewBayer CropScience, Monheim am Rhein, Germany.
Agim BallvoraInstitute of Crop Science and Resource Conservation (INRES), Plant Breeding, University of Bonn, Bonn, Germany.
Annaliese S MasonInstitute of Crop Science and Resource Conservation (INRES), Plant Breeding, University of Bonn, Bonn, Germany.
Jens LéonInstitute of Crop Science and Resource Conservation (INRES), Plant Breeding, University of Bonn, Bonn, Germany. j.leon@uni-bonn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marker assisted breeding, facilitated by reference genome assemblies, can help to produce cultivars adapted to changing environmental conditions. However, anomalous linkage disequilibrium (LD), where single markers show high LD with markers on other chromosomes but low LD with adjacent markers, is a serious impediment for genetic studies. We used a LD-correction approach to overcome these drawbacks, correcting the physical position of markers derived from 15 and 135 K arrays in a diversity panel of bread wheat representing 50 years of breeding history. We detected putative mismapping of 11.7% markers and improved the physical alignment of 5.4% markers. Population analysis indicated reduced genetic diversity over time as a result of breeding efforts. By analysis of outlier loci and allele frequency change over time we traced back the 2NS/2AS translocation of Aegilops ventricosa to one cultivar, "Cardos" (registered in 1998) which was the first among the panel to contain this translocation. A "selective sweep" for this important translocation region on chromosome 2AS was found, putatively linked to plant response to biotic stress factors. Our approach helps in overcoming the drawbacks of incorrectly anchored markers on the wheat reference assembly and facilitates detection of selective sweeps for important agronomic traits.

Identifiers

PMID33750919
PMCPMC7970893

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.