Evidence map›Paper›PMID 33750893›Full record

ArticleCommunications biology2021

Bmp8a is an essential positive regulator of antiviral immunity in zebrafish.

Shenjie Zhong, Haoyi Li, Yun-Sheng Wang, Ying Wang, Guangdong Ji, Hong-Yan Li, Shicui Zhang, Zhenhui Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. The Role of the CD28 Family Receptors in T-Cell Immunomodulation.International journal of molecular sciences · 2024
    Review
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Shenjie ZhongCollege of Marine Life Science and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.ORCID 0000-0003-0243-0584
Haoyi LiCollege of Marine Life Science and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.
Yun-Sheng WangCollege of Marine Life Science and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.
Ying WangCollege of Marine Life Science and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.
Guangdong JiCollege of Marine Life Science and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.
Hong-Yan LiCollege of Marine Life Science and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.ORCID 0000-0002-2191-1247
Shicui ZhangCollege of Marine Life Science and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China. sczhang@ouc.edu.cn.ORCID 0000-0002-7488-6487
Zhenhui LiuCollege of Marine Life Science and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China. zhenhuiliu@ouc.edu.cn.ORCID 0000-0002-2725-0101
Qingdao National Laboratory for Marine Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone morphogenetic protein (BMP) is a kind of classical multi-functional growth factor that plays a vital role in the formation and maintenance of bone, cartilage, muscle, blood vessels, and the regulation of adipogenesis and thermogenesis. However, understanding of the role of BMPs in antiviral immunity is still limited. Here we demonstrate that Bmp8a is a newly-identified positive regulator for antiviral immune responses. The bmp8a

Indexed as

AnimalsAnimals, Genetically ModifiedBone Morphogenetic Protein Receptors, Type IBone Morphogenetic ProteinsGene Knockout TechniquesHost-Pathogen InteractionsInterferon Regulatory Factor-3Interferon Type Ip38 Mitogen-Activated Protein KinasesPhosphorylationProtein Serine-Threonine KinasesRetroviridaeRetroviridae InfectionsSignal TransductionViral LoadVirus Replicationbmp8a protein, zebrafishBone Morphogenetic Protein Receptors, Type IBone Morphogenetic ProteinsInterferon Regulatory Factor-3Interferon Type IIrf3 protein, zebrafishp38 Mitogen-Activated Protein KinasesProtein Serine-Threonine Kinasestbk1 protein, zebrafishZebrafish Proteins

Identifiers

PMID33750893
PMCPMC7943762
OpenAlexW3149096324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.