ArticleNature communications2021
All-printed stretchable corneal sensor on soft contact lenses for noninvasive and painless ocular electrodiagnosis.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Thickness-Gradient Liquid Metal Connectors for Seamless Electrophysiological Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Electronics-Free Visual Monitoring of Dry Eye Disease-Related Tear Biomarkers Using Smart Scleral Lenses.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Nocturnal Intraocular Pressure Monitoring With a Soft Contact Lens Sensor for Glaucoma Management.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Photonic Nanomaterials for Wearable Health Solutions.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Bioinspired Intelligent Soft Robotics: From Multidisciplinary Integration to Next-Generation Intelligence.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Noninvasive On-Skin Biosensors for Monitoring Diabetes Mellitus.Nano-micro letters · 2025Review
- Kirigami-Inspired Breathable Smart Contact Lens for Wireless Monitoring of Corneal Hypoxia and Microenvironment.Advanced healthcare materials · 2025Article
- Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics.Advanced biology · 2025Review
- Effects of different anesthetic drugs on electroretinography in mice.Scientific reports · 2025Article
- Biomaterials for reliable wearable health monitoring: Applications in skin and eye integration.Biomaterials · 2025Review
- Advancements in Passive Wireless Sensing Systems in Monitoring Harsh Environment and Healthcare Applications.Nano-micro letters · 2025Review
- Microneedles for controlled and sustained intraocular drug delivery.NPG Asia materials · 2025Review
- Beyond Flexible: Unveiling the Next Era of Flexible Electronic Systems.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Wearable Sensors for Physiological Condition and Activity Monitoring.Small science · 2024Article
- Frequency-encoded eye tracking smart contact lens for human-machine interaction.Nature communications · 2024Article
- Advances in the Use of Conducting Polymers for Healthcare Monitoring.International journal of molecular sciences · 2024Review
- Advances and Opportunities of Mobile Health in the Postpandemic Era: Smartphonization of Wearable Devices and Wearable Deviceization of Smartphones.JMIR mHealth and uHealth · 2024Article
- Designs and Applications for the Multimodal Flexible Hybrid Epidermal Electronic Systems.Research (Washington, D.C.) · 2024Article
- Smart Contact Lenses as Wearable Ophthalmic Devices for Disease Monitoring and Health Management.Chemical reviews · 2023Review
- Mechanically-Guided 3D Assembly for Architected Flexible Electronics.Chemical reviews · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electroretinogram examinations serve as routine clinical procedures in ophthalmology for the diagnosis and management of many ocular diseases. However, the rigid form factor of current corneal sensors produces a mismatch with the soft, curvilinear, and exceptionally sensitive human cornea, which typically requires the use of topical anesthesia and a speculum for pain management and safety. Here we report a design of an all-printed stretchable corneal sensor built on commercially-available disposable soft contact lenses that can intimately and non-invasively interface with the corneal surface of human eyes. The corneal sensor is integrated with soft contact lenses via an electrochemical anchoring mechanism in a seamless manner that ensures its mechanical and chemical reliability. Thus, the resulting device enables the high-fidelity recording of full-field electroretinogram signals in human eyes without the need of topical anesthesia or a speculum. The device, superior to clinical standards in terms of signal quality and comfortability, is expected to address unmet clinical needs in the field of ocular electrodiagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.