Trial reportScientific reports2021
Impact of tDCS on working memory training is enhanced by strategy instructions in individuals with low working memory capacity.
Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Towards optimized methodological parameters for maximizing the behavioral effects of transcranial direct current stimulation.Frontiers in human neuroscience · 2024Pooled it
- Noninvasive Brain Stimulation over the Frontopolar Cortex Promotes Willingness to Exert Cognitive Effort in a Foraging-Like Sequential Choice Task.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Trial
- Transfer Effects of Integrated Adaptive Working Memory Training in School-Age Children: Improvements in Inhibitory Control and Asymmetric Gains in Mathematical Abilities.Journal of Intelligence · 2026Article
- Prefrontal TDCS does not improve working memory performance in individuals with chronic alcohol and tobacco use.IBRO neuroscience reports · 2026Article
- Mapping and modulating brain dynamics in aging and neurodegeneration with electroencephalography and integrated neurotechnologies in primates.Frontiers in neuroscience · 2026Review
- Dual-montage high-definition transcranial direct current stimulation (HD-tDCS) modulates the neural dynamics serving working memory.NeuroImage · 2025Article
- Lasting enhancements in neural efficiency by multi-session transcranial direct current stimulation during working memory training.NPJ science of learning · 2023Article
- Combined effect of transcutaneous auricular vagus nerve stimulation and 0.1 Hz slow-paced breathing on working memory.Frontiers in neuroscience · 2023Article
- Transcranial photobiomodulation enhances visual working memory capacity in humans.Science advances · 2022Article
- Training attentive individuation leads to visuo-spatial working memory improvement in low-performing older adults: An online study.Attention, perception & psychophysics · 2022Article
- Older adults with lower working memory capacity benefit from transcranial direct current stimulation when combined with working memory training: A preliminary study.Frontiers in aging neuroscience · 2022Article
- Non-invasive brain stimulation and neuroenhancement.Clinical neurophysiology practice · 2022Review
- Boosting working memory: uncovering the differential effects of tDCS and tACS.Cerebral cortex communications · 2022Article
- Event-Related Potentials as Markers of Efficacy for Combined Working Memory Training and Transcranial Direct Current Stimulation Regimens: A Proof-of-Concept Study.Frontiers in systems neuroscience · 2022Article
- Transcutaneous Auricular Vagus Nerve Stimulation Improves Spatial Working Memory in Healthy Young Adults.Frontiers in neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interventions to improve working memory, e.g. by combining task rehearsal and non-invasive brain stimulation, are gaining popularity. Many factors, however, affect the outcome of these interventions. We hypothesize that working memory capacity at baseline predicts how an individual performs on a working memory task, by setting limits on the benefit derived from tDCS when combined with strategy instructions; specifically, we hypothesize that individuals with low capacity will benefit the most. Eighty-four participants underwent two sessions of an adaptive working memory task (n-back) on two consecutive days. Participants were split into four independent groups (SHAM vs ACTIVE stimulation and STRATEGY vs no STRATEGY instructions). For the purpose of analysis, individuals were divided based on their baseline working memory capacity. Results support our prediction that the combination of tDCS and strategy instructions is particularly beneficial in low capacity individuals. Our findings contribute to a better understanding of factors affecting the outcome of tDCS when used in conjunction with cognitive training to improve working memory. Moreover, our results have implications for training regimens, e.g., by designing interventions predicated on baseline cognitive abilities, or focusing on strategy development for specific attentional skills.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.