Evidence map›Paper›PMID 33750424›Full record

ArticleJournal of orthopaedic surgery and research2021

The most appropriate titanium mesh cage size for anterior spinal reconstruction after single-level lumbar total en bloc spondylectomy: a finite element analysis and cadaveric validation study.

Permsak Paholpak, Winai Sirichativapee, Taweechok Wisanuyotin, Weerachai Kosuwon, Yuichi Kasai, Hideki Murakami

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Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 citing papers in PubMed.

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6 authors.

Permsak PaholpakDepartment of Orthopedics, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand. permpa@kku.ac.th.ORCID http://orcid.org/0000-0003-0826-306X
Winai SirichativapeeDepartment of Orthopedics, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Taweechok WisanuyotinDepartment of Orthopedics, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Weerachai KosuwonDepartment of Orthopedics, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Yuichi KasaiDepartment of Orthopedics, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Hideki MurakamiDepartment of Orthopedic Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is little information available regarding the cage diameter that can provide the most rigid construct reconstruction after total en bloc spondylectomy (TES). The aim of this study was thus to determine the most appropriate titanium mesh cage diameter for reconstruction after spondylectomy.

methodsA finite element model of the single level lumbar TES was created. Six models of titanium mesh cage with diameters of 1/3, 1/2, 2/3, 3/4, 4/5 of the caudad adjacent vertebra, and 1/1 of the cephalad vertebra were tested for construct stiffness. The peak von Mises stress (MPa) at the failure point and the site of failure were measured as outcomes. A cadaveric validation study also conducted to validate the finite element model.

resultsFor axial loading, the maximum stress points were at the titanium mesh cage, with maximum stress of 44,598 MPa, 23,505 MPa, 23,778 MPa, and 16,598 MPa, 10,172 MPa, 10,805 MPa in the 1/3, 1/2, 2/3, 3/4, 4/5, and 1/1 diameter model, respectively. For torsional load, the maximum stress point in each of the cages was identified at the rod area of the spondylectomy site, with maximum stress of 390.9 MPa (failed at 4459 cycles), 141.35 MPa, 70.098 MPa, and 88.972 MPa, 42.249 MPa, 15.827 MPa, respectively. A cadaveric validation study results were coincided with the finite element model results.

conclusionThe most appropriate mesh cage diameter for reconstruction is 1/1 the diameter of the lower endplate of the adjacent cephalad vertebra, due to its ability to withstand both axial and torsional stress. According to the difficulty of large size cage insertion, a cage diameter of more than half of the upper endplate of the caudad vertebrae is acceptable in term of withstand stress. A cage diameter of 1/3 is unacceptable for reconstruction after total en bloc spondylectomy.

Indexed as

Finite Element AnalysisProstheses and ImplantsProsthesis DesignSurgical MeshTitaniumBiomechanical PhenomenaBone TransplantationCadaverHumansLumbar VertebraeOsteotomyPlastic Surgery ProceduresSpinal NeoplasmsStress, MechanicalWeight-BearingTitaniumAnterior ReconstructionConstruct rigidityFinite element modelTitanium mesh cage diameterTotal en bloc spondylectomy; TES

Identifiers

PMID33750424
PMCPMC7941739

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.