Evidence map›Paper›PMID 33750348›Full record

ArticleBMC ophthalmology2021

Neonatal eye screening for 203 healthy term new-borns using a wide-field digital retinal imaging system.

Kenneth Teow Kheng Leong, Siti Nur Amira Abu Kassim, Jasvinjeet Kaur Sidhu, Zayani Zohari, Thivakar Sivalingam, Sunder Ramasamy, Safinaz Mohd Khialdin, Noraihan Mohd Nordin, Jamalia Rahmat

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kenneth Teow Kheng LeongDepartment of Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000, Cheras, Kuala Lumpur, Malaysia. kennethteow@yahoo.com.ORCID http://orcid.org/0000-0002-6883-9326
Siti Nur Amira Abu KassimDepartment of Ophthalmology, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur, Malaysia.
Jasvinjeet Kaur SidhuDepartment of Ophthalmology, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur, Malaysia.
Zayani ZohariDepartment of Ophthalmology, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur, Malaysia.
Thivakar SivalingamDepartment of Ophthalmology, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur, Malaysia.
Sunder RamasamyDepartment of Ophthalmology, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur, Malaysia.
Safinaz Mohd KhialdinDepartment of Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000, Cheras, Kuala Lumpur, Malaysia.
Noraihan Mohd NordinDepartment of Obstetrics & Gynaecology, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur, Malaysia.
Jamalia RahmatDepartment of Ophthalmology, Hospital Kuala Lumpur, 50586, Jalan Pahang, Kuala Lumpur, Malaysia.
Hospital Kuala Lumpur · MYUniversity Kebangsaan Malaysia Medical Centre · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current practice for new-born eye examination by an Ophthalmologist in Malaysian hospitals is limited to only preterm new-borns, syndromic or ill infants. Healthy term new-borns are usually discharged without a thorough eye examination. This study is aimed at determining the proportion and types of ocular abnormalities detected in purportedly healthy term new-borns.

methodThis cross-sectional study is comprised of 203 participants, all purportedly healthy term new-born infants from the Obstetrics and Gynaecology ward at Hospital Kuala Lumpur over a 6 months period. The examination list includes external eye examination, red reflex test, and fundus imaging using a wide-field digital retinal imaging system (Phoenix Clinical ICON Paediatric Retinal Camera) by a trained Investigator. The pathologies detected were documented. The results were compared and correlated with similar studies published in the literature previously.

resultsTotal ocular abnormalities were detected in 34% of the infants. The most common finding was retinal haemorrhage in 29.6% of the infants, of which 53.3% occurred bilaterally. Spontaneous vaginal delivery (SVD) remained the greatest risk factor which has nearly 3.5 times higher risk of new-borns developing retinal haemorrhage compared to Lower Segment Caesarean Section (LSCS). There was a 6% increased likelihood of developing retinal haemorrhage for every 1-min increment in the duration of 2nd stage of labour.

conclusionUniversal eye screening for all new-borns using a wide-field digital imaging system is realistically possible, safe, and useful in detecting posterior segment disorders. The most common abnormality detected is retinal haemorrhage.

Indexed as

Cesarean SectionNeonatal ScreeningChildCross-Sectional StudiesFemaleFundus OculiHumansInfantInfant, NewbornPregnancyRetinaEye screeningHaemorrhageHealthyNew-bornTermUniversal

Identifiers

PMID33750348
PMCPMC7941744
OpenAlexW3136636162

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.