ArticleBMC gastroenterology2021
Clinical characteristics of acute pancreatitis in children: a single-center experience in Western China.
Article in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Acute and Recurrent Pancreatitis in Children: Insights into Etiology and Clinical Course from a Retrospective Single-Center Study.Children (Basel, Switzerland) · 2026Article
- Phenotype, Management, and Outcomes in Paediatric Acute Pancreatitis: A Real-Life Cross-Sectional Study.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Genotype-Phenotype Correlations in Pediatric Hereditary Pancreatitis: Evidence from a Romanian Retrospective Cohort.Journal of clinical medicine · 2026Article
- Progression from acute to chronic pancreatitis in children: a systematic review and meta-analysis.Clinical and experimental pediatrics · 2026Article
- Global, regional and national burden of pancreatitis in children and adolescents, 1990-2021: a systematic analysis for the global burden of disease study 2021.Annals of medicine · 2025Article
- Obesity alters metabolic profiles in children with acute pancreatitis, but not disease severity and recurrence: a Romanian cohort study.Archive of clinical cases · 2025Article
- Review of acute pancreatitis in children in India.Journal of family medicine and primary care · 2024Review
- Incidence of recurrent and chronic pancreatitis after acute pancreatitis: a systematic review and meta-analysis.Therapeutic advances in gastroenterology · 2024Article
- Lethal hemorrhagic necrotizing pancreatitis in a child with congenital immunodeficiency and COVID-19.Journal of pediatric surgery case reports · 2022Article
- Article
- Acute Pancreatitis and Recurrent Acute Pancreatitis in Children: A 10-Year Retrospective Study.Gastroenterology research and practice · 2022Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe diagnosis of pediatric pancreatitis has been increasing over the last 20 years. We aimed to compare the clinical characteristics for pediatric acute pancreatitis (AP) with adult AP, and investigate the risk factor for acute recurrent pancreatitis (ARP) in children.
methodFrom June 2013 to June 2019, a total of 130 pediatric patients with AP at the inpatient database were enrolled. Univariate analysis and multivariate Cox regression analysis were performed to identify the risk factors for ARP in children.
resultMajor etiologic factors in 130 patients were biliary (31.5%), idiopathic (28.5%). The etiology of pancreatitis in children was markedly different from that in adults (p < 0.001). Compared with the adult patients, the pediatric patients had significantly lower severity (p = 0.018) and occurrence rate of pancreatic necrosis (p = 0.041), SIRS (p = 0.021), acute peripancreatic fluid collection (p = 0.014). Univariate and Multivariate Cox regression analysis showed that female (p = 0.020; OR 3.821; 95% CI 1.231-11.861), hypertriglyceridemia (p = 0.045; OR 3.111; 95% CI 1.024-9.447), pancreatic necrosis (p = 0.023; OR 5.768; 95% CI 1.278-26.034) were the independent risk factors of ARP. Hypertriglyceridemia AP had the highest risk of recurrence compared to other etiology (p = 0.035).
conclusionBiliary and idiopathic disease were the major etiologies of AP in children. Children have simpler conditions than adults. Female, hypertriglyceridemia, and pancreatic necrosis were associated with the onset of ARP.
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